Results 41 to 50 of about 257 (174)

Value‐based prices of emerging disease‐modifying therapies for Alzheimer's disease in 174 countries: a cost‐effectiveness and threshold analysis

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Countries have varying, limited healthcare budgets for emerging disease‐modifying therapies. Cost‐effectiveness analysis, combined with country‐level cost‐effectiveness thresholds, can be used to estimate value‐based prices (VBPs) for lecanemab and donanemab across 174 countries.
Men Thi Hoang   +3 more
wiley   +1 more source

Evidence for different seeding activities of misfolded tau in classical and rapidly progressive Alzheimer's disease

open access: yesBrain Pathology, Volume 36, Issue 3, May 2026.
The study analyzed the seeding activity of misfolded tau protein in Alzheimer's disease and rapidly progressive Alzheimer's disease patients and provides evidence for the existence of different tau assemblies supported by differences in cellular toxicity and morphology of thioflavin T‐positive real‐time quaking‐induced conversion products.
Matthias Schmitz   +13 more
wiley   +1 more source

Benchmarking speech biomarkers of Alzheimer's against cognitive and neural measures

open access: yesAlzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Digital speech biomarkers (DSBs) support the detection and monitoring of Alzheimer's disease (AD) in Latinos. However, they have not been benchmarked against standard cognitive and neuroimaging measures, missing a critical validation milestone. METHODS Thirty‐three AD patients and 33 healthy controls completed verbal fluency tasks,
Ivan Caro   +15 more
wiley   +1 more source

Adaptive Channel-Tracking Method and Equalization for MC-CDMA Systems over Rapidly Fading Channel under Colored Noise

open access: yesEURASIP Journal on Advances in Signal Processing, 2010
A recursive maximum-likelihood (RML) algorithm for channel estimation under rapidly fading channel and colored noise in a multicarrier code-division multiple-access (MC-CDMA) system is proposed in this paper. A moving-average model with exogenous input (
Chen Bor-Sen, Yang Chang-Yi
doaj  

NARROWBAND INTERFERENCE REDUCTION TECHNIQUE IN IMPULSE RADIO (IR) UWB COMMUNICATION SYSTEM COEXISTING IN WPAN AND UNDERWATER ENVIRONMENT [PDF]

open access: yesICTACT Journal on Communication Technology, 2012
The Impulse Radio based Ultra Wideband (IR-UWB) system transmits data by sending pulses, each with very small time duration followed by pauses that are approximately two hundred times that length.
Bikramaditya Das   +4 more
doaj  

Minimum Probability of Error-Based Equalization Algorithms for Fading Channels

open access: yesEURASIP Journal on Wireless Communications and Networking, 2007
Novel channel equalizer algorithms are introduced for wireless communication systems to combat channel distortions resulting from multipath propagation.
van der Meulen Edward C   +2 more
doaj   +2 more sources

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

Modulation of Non‐Rhythmic Temporal Prediction by Subthalamic Nucleus Deep Brain Stimulation (STN‐DBS) in Parkinson's Disease

open access: yesMovement Disorders, Volume 41, Issue 4, Page 992-1003, April 2026.
Background Accurate temporal prediction, essential for adaptive motor behavior, relies on corticobasal ganglia circuits. In Parkinson's disease (PD), both motor and non‐motor functions are impaired. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) effectively alleviates motor symptoms, but its effects on non‐motor domains, like temporal ...
Rebecca Burke   +5 more
wiley   +1 more source

Exploring small‐world brain connectivity in aging and its relationship with cognitive reserve

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 2, April/June 2026.
Abstract INTRODUCTION The aging brain's vulnerability to decline emphasizes the importance of strategies preserving cognitive function and independence. As age‐related brain changes do not always match clinical symptoms, reserve, encompassing brain reserve (BR) and cognitive reserve (CR), has emerged as a key mechanism supporting resilience and ...
Chiara Pappalettera   +13 more
wiley   +1 more source

Vagus nerve stimulation alters task‐evoked pupillary responses in older but not younger adults: A single‐blind active sham‐controlled crossover trial

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The locus coeruleus (LC) undergoes age‐related changes and is involved in Alzheimer's disease pathogenesis. Vagus nerve stimulation (VNS) may modulate LC activity and could be used therapeutically, but age‐related differences in VNS responses remain unexplored.
Elizabeth Riley   +4 more
wiley   +1 more source

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