Investigating the Role of Neutrophil Extracellular Traps as a Therapeutic Target in Traumatic Brain Injury: a Systematic Review and Meta-analysis. [PDF]
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality worldwide, with few treatment options to mitigate secondary injury. Neutrophil extracellular traps (NETs) may present a potential target for therapy.
Slough E +5 more
europepmc +3 more sources
No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Bohmann, Ferdinand +6 more
core +14 more sources
Identification of the Kna/Knb polymorphism and a method for Knops genotyping [PDF]
BACKGROUND: DNA mutations resulting in the McCoy and Swain-Langley polymorphisms have been identified on complement receptor 1 (CR1)—a ligand for rosetting of Plasmodium falciparum-infected RBCs.
Daniels +17 more
core +1 more source
OBJECTIVE: To implement genotyping for S, s and U antigens of the MNS blood group system at the Fundação Hemominas and to evaluate the occurrence of GYPB gene polymorphisms associated with the U- and U+var phenotypes and deletion of the GYPB gene for the
Marina Alves Faria +3 more
doaj +1 more source
Red cell phenotyping of blood from donors at the National blood center of Malaysia
Background : Human blood groups are polymorphic and inherited integral structures of the red cell membrane. More than 300 red cell antigens have been identified and further categorized into 30 major discrete systems.
Rozi H Musa +6 more
doaj +1 more source
The anti-Mia antibody – Report of four cases in a tertiary care hospital with review of literature
Anti – Mia antibody is antibody reacting with Mi III phenotype of the Miltenberger (Mi) subsystem. It is rarely reported in the West, however, it is common in Chinese and South East Asian populations. Very few cases have been reported in India.
Sangeeta Pahuja +4 more
doaj +1 more source
NogoA neutralization promotes axonal restoration after white matter injury in subcortical stroke [PDF]
Blocking axonal growth inhibitor NogoA has been of great interest for promoting axonal recovery from neurological diseases. The present study investigates the therapeutic effects of blocking NogoA, inducing functional recovery and promoting white matter ...
core +1 more source
Transient but not permanent benefit of neuronal progenitor cell therapy after traumatic brain injury: potential causes and translational consequences [PDF]
Background:: Numerous studies have reported a beneficial impact of neural progenitor cell transplantation on functional outcome after traumatic brain injury (TBI) during short and medium follow-up periods.
Franziska eScheidt +9 more
core +3 more sources
AT 1 inhibition mediated neuroprotection after experimental traumatic brain injury is dependent on neutrophils in male mice [PDF]
After traumatic brain injury (TBI) cerebral inflammation with invasion of neutrophils and lymphocytes is a crucial factor in the process of secondary brain damage.
Coronel-Castello, Shila P. +6 more
core +1 more source
Isofuranodiene, a natural sesquiterpene isolated from wild celery (Smyrnium olusatrum L.), protects rats against acute ischemic stroke [PDF]
The myrrh-like furanosesquiterpene isofuranodiene (IFD) is the main constituent of wild celery (Smyrnium olusatrum L., Apiaceae), an overlooked vegetable that was cultivated during the Roman Empire.
A. R. Dehpour +10 more
core +1 more source

