Results 141 to 150 of about 5,670,979 (332)

Managing Dairy Heifer Growth Investment [PDF]

open access: yes
Accelerated prepubertal growth rates can lower heifer raising costs but may put heifers at risk for impaired mammary development and have been found to be detrimental decreased to milk production in the first lactation.
Hadrich, Joleen C.   +2 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

First observation of Λb0Σc(*)++D(*)K decays

open access: yesPhysical Review
The four decays, Λb0→Σc(*)++D(*)−K−, are observed for the first time using proton-proton collision data collected with the LHCb detector at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 6 fb−1. By considering the Λb0→Λc+D¯0K− decay as reference channel, the following branching fraction ratios are measured to be B(Λb0 ...
Aaij, R.   +199 more
openaire  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Bosonic algebraic approach applied to the [QQ][Q¯Q¯] tetraquarks

open access: yesPhysical Review, 2022
The exact eigenenergies of the T4c=[cc][c¯c¯], T4b=[bb][b¯b¯], and T2[bc]=[bc][b¯c¯] tetraquarks are calculated within the extended transitional Hamiltonian approach, in which the so-called Bethe ansatz within an infinite-dimensional Lie algebra is used.
Majarshin, A. J.   +3 more
openaire  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Electrical Resistivity Modification of Electrodeposited Mo and Mo–Co Nanowires for Interconnect Applications

open access: yesEngineering
Achieving historically anticipated improvement in the performance of integrated circuits is challenging, due to the increasing cost and complexity of the required technologies with each new generation.
Jun Hwan Moon   +8 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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