Results 241 to 250 of about 58,944 (350)

Integrating Nuclear Magnetic Resonance into Bioprocess Control of Clinical‐Grade Extracellular Vesicle Manufacturing

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
Nuclear magnetic resonance (NMR) in bioprocess design for the production of extracellular vesicles (EVs). NMR‐metabolomics enables real‐time bioprocess intelligence, bridging biological complexity with GMP rigor and accelerating the clinical translation of EV‐based therapies.
Santiago Roura   +2 more
wiley   +1 more source

Regulatory Challenges and Opportunities for Cell‐Derived Extracellular Vesicles in Pharmaceutical Development: A European and Global Perspective

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
EV‐based therapeutics are advancing worldwide, but regulatory classification and development expectations remain inconsistent across jurisdictions. This review maps challenges in quality, potency, comparability, safety, clinical design, and ethical/legal oversight, and argues for consistent use of existing medicinal‐product frameworks. We emphasize the
Tania Limongi   +3 more
wiley   +1 more source

molIEreVIS: exploring and interpreting the evidence behind drug repurposing predictions. [PDF]

open access: yesFront Bioinform
Alnouri A   +7 more
europepmc   +1 more source

Generative Artificial Intelligence and Large Language Models in Clinical Oncology

open access: yesMedComm, Volume 7, Issue 7, July 2026.
By integrating multimodal data, including medical imaging, pathology, omics, and electronic health records, generative AI and LLMs support cancer diagnosis, treatment planning, and follow‐up management. These technologies also enhance physician–patient communication, improve personalized treatment strategies, and leverage intelligent agent automation ...
Yunfang Yu   +14 more
wiley   +1 more source

Integrated genomic and transcriptomic approaches reveal oxidative stress adaptation mechanisms in a mesotrione‐resistant Amaranthus tuberculatus biotype

open access: yesPest Management Science, Volume 82, Issue 7, Page 6387-6398, July 2026.
Integrated GWAS and transcriptomics in a Canadian waterhemp biotype reveal mesotrione resistance is polygenic and metabolically driven. Significant SNPs and 187 herbicide‐responsive genes point to enhanced redox homeostasis, glutathione‐linked detoxification, lipid/secondary metabolism, and oxidative stress responses. Resistance arises from coordinated,
Martin Laforest   +6 more
wiley   +1 more source

Large-Scale Chemical-Genetic Interaction Profiling Identifies a Small-Molecule Inhibitor of <i>Mycobacterium tuberculosis</i> Polyketide Synthase 13. [PDF]

open access: yesACS Infect Dis
Gomez JE   +9 more
europepmc   +1 more source

Thirty years of glyphosate‐resistant crops and weeds: Current situation and future prospects

open access: yesPest Management Science, Volume 82, Issue 7, Page 5987-6009, July 2026.
Since 1996, when the first glyphosate‐resistant crop was commercialized and the first resistant weed was reported, resistance has expanded globally. This review analyzes emergence patterns across weed species, crops, regions, resistance mechanisms, and herbicides.
Ricardo Alcántara‐de la Cruz   +7 more
wiley   +1 more source

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