Results 71 to 80 of about 4,091,586 (279)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Nuove applicazioni di Realtí Aumentata per il learning by interacting.
Archeomatica, 2017 The adoption of innovative tools and new chains of digitization, represent an unavoidable base of knowledge towards a more clear understanding of our cultural heritage.
Paolo Clini +4 more
doaj +1 more source
, 2000 We explore the properties of the bipolaron in a 1D Holstein-Hubbard model with dynamical quantum phonons. Using a recently developed variational method combined with analytical strong coupling calculations, we compute correlation functions, effective ...
Bonca, J., Katrasnik, T., Trugman, S. A.
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
An Investigation into Mobile Based Approach for Healthcare Activities, Occupational Therapy System [PDF]
, 2013 This research is to design and optimize the high quality of mobile apps, especially for iOS. The objective of this research is to develop a mobile system for Occupational therapy specialists to access and retrieval information.
Lu, Joan, Mahmood, Sardasht
core
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Development tools for mobile devices in market price information systems [PDF]
, 2005 There are already several applications on mobile devices that can be useful in agriculture. For example: GPS-enabled map software, individual cattle identification and tracking software and even complex agricultural systems. These are just beginning to
Herdon, Miklós +2 more
core
When Mobile Blockchain Meets Edge Computing
, 2018 Blockchain, as the backbone technology of the current popular Bitcoin digital currency, has become a promising decentralized data management framework.
Han, Zhu +4 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source