Results 81 to 90 of about 4,091,586 (279)
Background Novel interventions are needed to improve lifestyle and prevent noncommunicable diseases, the leading cause of death and disability globally. This study aimed to systematically review, synthesize, and grade scientific evidence on effectiveness
Ashkan Afshin +7 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Radiology and the mobile device: Radiology in motion
The use of mobile devices is revolutionizing the way we communicate, interact, are entertained, and organize our lives. With healthcare in general and radiology in particular becoming increasingly digital, the use of such devices in radiologic practice ...
Sridhar G Panughpath, Arjun Kalyanpur
doaj +1 more source
Submission to the Attorney-General’s Department on the Exposure Draft Telecommunications and Other Legislation Amendment Bill 2015 [PDF]
EXECUTIVE SUMMARY As has been stated in previous submissions to Government, the Associations acknowledge Government’s desire to protect telecommunications infrastructure and the information transmitted across it from unauthorised access and ...
Australian Industry Group +3 more
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
English Vocabulary Apps for Classroom Use? Results of an Empirical Survey
Mobile apps (applications) are currently taking over as our most frequently used tools in many situations. As teachers we need to consider whether they ought to be employed in the language classroom, allowed in tests, or referred to for homework.
Danijela Ikonic, Thomas Hawes
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Exploring the use of mobile learning amongst the dental students of Tehran University of medical sciences [PDF]
Introduction: Covid-19 pandemic has underscored the importance of e-learning. This study endeavors to determine the extent and the way of using mobile learning amongst dental students. Methods: This descriptive study is cross-sectional.
Maryam Koopaie +2 more
doaj
Morpes: A Model for Personalized Rendering of Web Content on Mobile Devices
With the tremendous growth in the information communication sector, the mobile phones have become the prime information communication devices. The convergence of traditional telephony with the modern web enabled communication in the mobile devices has ...
Aghila, G., Kuppusamy, K. S.
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

