Results 51 to 60 of about 8,763,249 (336)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Mobile devices and localization

Procedia Computer Science, 2011
AbstractIt is obvious, that the use of mobile technology in general represents a great asset for the company’s competitive ability. The greatest barriers for installation of mobile technology might be financial difficulties, negative approach of managers and employees, and also the fact, that the character of the company allows no or minimal use of ...
openaire   +2 more sources

Digital disruption?: Maternal mobile device use is related to infant social-emotional functioning

Developmental Science, 2017
Mobile device use has become increasingly prevalent, yet its impact on infant development remains largely unknown. When parents use mobile devices in front of infants, the parent is physically present but most likely distracted and unresponsive. Research
Sarah Myruski, Olga Gulyayeva, Samantha L. Birk, Koraly Pérez-Edgar, K. Buss, T. Dennis-Tiwary   +5 more
semanticscholar   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Intelligent mobile user profile classification for content personalisation [PDF]

, 2009
Mobile device can be used as a medium to send and receive mobile internet content. Although there are several limitations using mobile internet, content personalisation have been viewed as an important area for advancing mobile internet. In this paper we
Wong, K.W., Paireekreng, W.
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Toward subtle intimate interfaces for mobile devices using an EMG controller [PDF]

, 2005
Using a mobile device in a social context should not cause embarrassment and disruption to the immediate environment. Interaction with mobile and wearable devices needs to be subtle, discreet and unobtrusive.
Costanza, Enrico, Samuel A. Inverso, Enrico Costanza, Rebecca Allen, Inverso, Samuel A., Allen, Rebecca   +5 more
core   +2 more sources

DTDNet: Dynamic Target Driven Network for pedestrian trajectory prediction

Frontiers in Neuroscience
Predicting the trajectories of pedestrians is an important and difficult task for many applications, such as robot navigation and autonomous driving. Most of the existing methods believe that an accurate prediction of the pedestrian intention can improve
Shaohua Liu, Jingkai Sun, Jingkai Sun, Pengfei Yao, Pengfei Yao, Yinglong Zhu, Yinglong Zhu, Tianlu Mao, Zhaoqi Wang   +8 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source