Results 211 to 220 of about 376,338 (268)

FAIM modulates HCC progression via enhancing HMGA1 interaction with CDK7 and promoting its phosphorylation level. [PDF]

J Transl Med
Li Y, Liu W, Fan X, Wu X, Cao M, Li X, Wurita A, Sun S.   +7 more
europepmc   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Plasma and Muscle Pharmacokinetics of Ceftriaxone in Nile Tilapia (<i>Oreochromis niloticus</i>) After Different Administration Routes. [PDF]

Antibiotics (Basel)
Marín P, Corum O, Corum DD, Badillo E, Yuste MT, Yildirim O, Terzi E, Gonzales RC, Arriesgado DM, Navarro VR, Uney K.   +10 more
europepmc   +1 more source

Reconfigurable Acoustofluidic Microvortices for Selective Microcargo Delivery

Advanced Science, EarlyView.
This work introduces a frequency‐encoded, reconfigurable acoustofluidic system that overcomes the low throughput and poor selectivity of conventional micro‐delivery methods. By exploiting discrete microbubble resonances to program adaptive microvortex modes, the platform enables real‐time switching and selective guidance of microscale payloads through ...
Lei Wang, Yiqiang Wu, Yiyang Tang, Hui Wei, Tianshi Lyu, Xin Zhang, Tian‐Yun Huang   +6 more
wiley   +1 more source

Design of an Automated Mobile Phone-Based Reminder and Incentive System: Application in a Quasi-Randomized Controlled Trial to Improve the Timeliness of Childhood Vaccinations in Tanzania. [PDF]

JMIR Form Res
van Zwetselaar M, Ostermann J, Beti M, Baumgartner JN, Mfinanga S, Ngadaya E, Vasudevan L, Thielman N.   +7 more
europepmc   +1 more source

AlF3 Mediated In‐Situ Cathode Interface Stabilization Enables High‐Rate and Long‐Life Na‐Ion Batteries at Elevated Temperature

Advanced Science, EarlyView.
Ultrathin AlF3 coating facilitates the formation of an inorganic‐dominated cathode electrolyte interphase (CEI), predominantly composed of NaF/AlF3/NaAlF4. This CEI layer effectively suppresses detrimental interfacial side reactions while simultaneously enhancing the diffusion kinetics of Na+.
Ya‐Meng Yin, Qinxia Liu, Zhiyuan Zhang, Weixiao Wang, Cunyuan Pei, Fangyu Xiong, Jinghui Chen, Qinyou An, Cai‐Hong Yang, Dong‐Sheng Li   +9 more
wiley   +1 more source

Using Dopants as Agents to Probe Key Electronic Properties of Organic Semiconductors

Advanced Electronic Materials, EarlyView.
Dopants are typically used in organic electronics to enhance conductivity, but here their potential is demonstrated as probes for fundamental material properties. By integrating experimental data and multiscale simulations, it is shown how dopant ionization and conductivity measurements enable accurate extraction of ionization potential and Coulomb ...
Artem Fediai, Franz Symalla, Tobias Neumann, Wolfgang Wenzel   +3 more
wiley   +1 more source

High-Throughput Quantification and Characterization of Dual Payload mRNA/LNP Cargo via Deformulating Size Exclusion and Ion Pairing Reversed Phase Assays. [PDF]

Anal Chem
Imiołek M, Cojocaru R, Fekete S, Le Huray J, Lauber M.   +4 more
europepmc   +1 more source

The Platform to Characterizing the Thermoelectric Materials by Photo‐Crosslinked Ionic Gel Electrolyte

Advanced Electronic Materials, EarlyView.
The device platform, which utilizes a photo‐crosslinked ionic gel electrolyte with a broad range of oxidation and reduction capabilities, can effectively evaluate and screen the thermoelectric material candidates with high potential across a wide range of doping levels, thereby minimizing the effort required to identify dopants compatible with ...
Sunbin Hwang, Mutsunori Uenuma, Junya Kurumida   +2 more
wiley   +1 more source