Results 241 to 250 of about 2,016,645 (349)

A focus on salts dissolved in salts: ionic liquid mixtures - ion pairs, ion pairing and ionic liquids. [PDF]

Chem Sci
Welton T.
europepmc   +1 more source

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

Advanced Science, EarlyView.
A peptide that replicates the amino acid sequence in Insig1/2 loop 1 inhibits the IGF1‐induced interaction between PCK1 and Insig1/2, PCK1‐mediated phosphorylation of Insig1/2, and SREBP activity‐dependent lipid synthesis. Administration of the LNP‐Insig1/2 loop 1 peptide effectively attenuates tumor growth and sensitizes tumors to the antitumor effect
Shudi Luo, Huang Yang, Xiaoming Jiang, Zheng Wang, Xuxiao He, Ying Meng, Shan Li, Min Li, Daqian Xu, Zhengwei Mao, Zhimin Lu   +10 more
wiley   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Expanding the Analytical Toolbox for the Nondenaturing Analysis of siRNAs with Salt-Mediated Ion-Pair Reversed-Phase Liquid Chromatography. [PDF]

Anal Chem
Enmark M, Furlan I, Habibollahi P, Manz C, Fornstedt T, Samuelsson J, Örnskov E, Jora M.   +7 more
europepmc   +1 more source

SP3 and DEP1 Orchestrate Panicle Architecture by Jointly Regulating APO2 Expression in Rice

Advanced Science, EarlyView.
The transcription factor SP3 enhances inflorescence meristem activity and interacts with the cysteine‐rich domain of DEP1. This interaction alters DEP1's subcellular localization between the plasma membrane and nucleus, and suppresses SP3‐mediated transcriptional activation of APO2.
Yuexin Liu, Niannian Chen, Xiaowei Fan, Xueqing Xia, Yilong Yao, Wen Huang, Jin Sun, Lintao Huang, Lei Wang, Hong Yu, Jiayang Li, Yongzhong Xing   +11 more
wiley   +1 more source

Solvent‐Rich Pre‐Coagulation Bath for Tunable Liquid‐State Fusion Enables Robust Two‐Step Polymer Embedded Printing

Advanced Science, EarlyView.
Additive manufacturing enables complex structures, but polymer printing often suffers from poor interlayer fusion and defects induced by heat or binders. A two‐step, room‐temperature strategy based on immersion phase separation (IPS‐E3DP) achieves precise liquid‐state fusion with high structural fidelity, enhanced mechanical performance, broad material
Kaidong Song, Qian Wu, Ashley M. Compaan, Junting Shen, Chuanshen Zhou, Mingwei Chen, Marc Sole‐Gras, John‐Thomas T. Robinson, Bing Ren, Huayong Yang, Yong Huang, Jun Yin   +11 more
wiley   +1 more source

Physicochemical and functional assessment of messenger RNA 5'Cap-end impurities under forced degradation conditions. [PDF]

Mol Ther Nucleic Acids
Hutchinson J, Schweikart F, Shannon R, Murthy A, Bates SM, Leone S, Nissan T, Sideris D, Lal C, Button J, Rani R, Thom G, Bond N, Örnskov E, Trabulo S.   +14 more
europepmc   +1 more source

La gestion dynamique de la qualité de service dans les réseaux IP mobiles

, 2006
Badr Benmammar
openalex   +1 more source

The CtrCBL1/CtrCIPK6 Complex of Citrus Phosphorylates CtrBBX32 to Regulate CtrSTP1‐Mediated Sugar Accumulation and Cold Tolerance

Advanced Science, EarlyView.
The CtrCBL1‐CtrCIPK6 module of trifoliate orange (Citrus trifoliata L.) phosphorylates CtrBBX32, triggering its protein degradation under cold conditions, thereby relieving CtrBBX32‐mediated transcriptional repression of CtrZAT10 and CtrSTP1. The consequent upregulation of CtrZAT10 further activates CtrSTP1 expression, which enhances hexose transport ...
Xiangming Shang, Zeqi Zhao, Wei Xiao, Yike Zeng, Mengdi Li, Xin Jiang, Bachar Dahro, Lele Chu, Min Wang, Chunlong Li, Ji‐Hong Liu   +10 more
wiley   +1 more source