Results 251 to 260 of about 2,016,645 (349)

Enhanced Superconductivity in X4H15 Compounds via Hole‐Doping at Ambient Pressure

Advanced Science, EarlyView.
Hole doping in X4H15 hydrides significantly enhances superconductivity, with X3 + compounds reaching Tc values near 50 K due to strong electron–phonon coupling. A viable route is proposed by doping thermodynamically unstable X43+H${\rm X}^{3+}_4{\rm H}$15 to control the charge‐compensated YZr3H15 compound.
Kun Gao, Wenwen Cui, Tiago F. T. Cerqueira, Hai‐Chen Wang, Silvana Botti, Miguel A. L. Marques   +5 more
wiley   +1 more source

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair. [PDF]

Nucleic Acids Res
Inanc B, Fang Q, Roos WP, Andrews JF, Zeng X, Clark J, Li J, Dey NB, Ibrahim M, Sykora P, Yu Z, Pearson CR, Braganza A, Verheij M, Jonkers J, Yates NA, Vens C, Sobol RW.   +17 more
europepmc   +1 more source

Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis

Advanced Science, EarlyView.
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu, Yan Zhu, Xinyi Jiang, Xiangzheng Zhang, Bing Wang, Yu Chen, Yichen Zhao, Yulian Wang, Qi Zhou, Zhongyan Han, Yaling Qi, Mengjiao Luo, Haixia Tu, Bingjie Hao, Mengmeng Gao, Jie Ren, Xin Zhou, Xingyu Zhang, Xu Chen, Haojie Li, Qian Huang, Chenghao Situ, Yueshuai Guo, Hui Zhu, Yan Li, Xuejiang Guo   +25 more
wiley   +1 more source

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang, Yanqiong Zhang, Sarah E. Rowe, Lupeng Li, Laura E. Herring, Brian P. Conlon, Edward A. Miao, Blossom Damania, Anna Mae Diehl, Pengda Liu   +14 more
wiley   +1 more source

Occupational health equity: a call to consider social-structural factors in injury prevention research. [PDF]

Inj Prev
Guillot-Wright S, McClure ES, Ramirez MR, Grimes Trotter A, Richardson DB.   +4 more
europepmc   +1 more source

Donnan‐Engineered Inner Helmholtz Plane Enabling Ultra‐Stable Aqueous Bismuth Electrode

Advanced Science, EarlyView.
A Donnan‐effect‐mimetic inner Helmholtz plane (IHP) can stabilize aqueous Bismuth electrodes through two synergistic mechanisms: i) charge‐selective ion partitioning that enriches Na⁺ while excluding OH⁻, enabling preferential (de)alloying over corrosive side reactions; and ii) electron confinement via the Donnan potential, which effectively suppresses
Tingting Qin, Wenli Zhang, Dong Wang, Yingguang Zhang, Taowen Dong, Zibo Zhang, Sarah K.W. Leong, Weichen Chen, Samy Mahmoud, Hanqing Liu, Yifei Wang, Xiaolong Zhao, Wei Dong, Meng Ni, Dennis Y.C. Leung, Zhenbin Guo, Wending Pan   +16 more
wiley   +1 more source

Ultrahigh Strength and Exceptional Work Hardening in a Hierarchical‐Structured Alloy via Hetero‐Interface‐Mediated Twinning

Advanced Science, EarlyView.
This study presents a novel strategy for achieving exceptional work hardening in ultrahigh‐strength alloys by designing hierarchically heterogeneous dual‐phase (HHDP) structures, where hetero‐deformation‐induced strain gradients activate deformation twinning.
Yitong Yang, Jingyu Pang, Hongwei Zhang, Jiajia Shen, Zhenqiang Xing, Yuan Sun, Aimin Wang, J. P. Oliveira, Wei Wang, Zengbao Jiao   +9 more
wiley   +1 more source

ERβ/circAHNAK Axis Inhibits USP10–FMR1 Deubiquitination to Prevent m⁶A‐Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In clear cell renal cell carcinoma, estrogen receptor β (ERβ) upregulates circAHNAK, which competitively binds USP10 to prevent FMR1 deubiquitination, leading to FMR1 degradation. Loss of FMR1 hinders m⁶A‐dependent decay of ADAM17 mRNA, resulting in ADAM17 accumulation in tumor exosomes and enhanced angiogenesis.
Chao Xu, Sujing Zhang, Yuepeng Liu, Jingwei Lv, Yilong Cao, Yao Chen, Hao Sun, Bowei Zhang, Shengtao Dai, Jiehan Li, Xiaoling Li, Bei Shi, Qingyun Sun, Meng Zhu, Junfei Gu   +14 more
wiley   +1 more source

A Co-Operative Perception System for Collision Avoidance Using C-V2X and Client-Server-Based Object Detection. [PDF]

Sensors (Basel)
Park J, Kavathekar V, Bhuduri S, Amin MH, Devaraj SS.   +4 more
europepmc   +1 more source