Results 251 to 260 of about 1,683,476 (303)

Blocking ITGA5 potentiates the efficacy of anti‐PD‐1 therapy on glioblastoma by remodeling tumor‐associated macrophages

Cancer Communications, EarlyView.
Abstract Background Glioblastoma (GBM) is largely refractory to antibodies against programmed cell death 1 (anti‐PD‐1) therapy. Fully understanding the cellular heterogeneity and immune adaptations in response to anti‐PD‐1 therapy is necessary to design more effective immunotherapies for GBM.
Rongrong Zhao, Ziwen Pan, Jiawei Qiu, Boyan Li, Yanhua Qi, Zijie Gao, Wei Qiu, Weijie Tang, Xiaofan Guo, Lin Deng, Gang Li, Hao Xue   +11 more
wiley   +1 more source

The interactive use of augmented reality for educating the elderly on common age-related eye disease. [PDF]

BMC Geriatr
Hung YY, Chu WY, Jiang J, Yeung WY, Yan WH, Kwok TO, Chan YK.   +6 more
europepmc   +1 more source

Decentralized Clinical Trials in the Era of Real-World Evidence: A Statistical Perspective. [PDF]

Clin Transl Sci
Chen J, Di J, Daizadeh N, Lu Y, Wang H, Shen YL, Kirk J, Rockhold FW, Pang H, Zhao J, He W, Potter A, Lee H.   +12 more
europepmc   +1 more source

SAAP‐148 Oligomerizes into a Hexamer Forming a Hydrophobic Inner Core

ChemBioChem, EarlyView.
The highly cationic and hydrophobic antimicrobial peptide SAP‐148 effectively eradicates multidrug‐resistant bacteria, persistent cells, and biofilms without inducing resistance. Its efficiency is likely due to its ability to disrupt bacterial membranes as an oligomer, forming a stable alpha‐helical hexameric bundle with three parallel dimers that ...
Aden Hodzic, Djenana Vejzovic, Altea Topciu, Kirill Kuhlmann, Raj Kumar, Maria Andrea Mroginski, Alejandra de Miguel, Pia Hofmann, Klaus Zangger, Markus Weingarth, Robert A. Cordfunke, Jan W. Drijfhout, Peter Nibbering, Michal Belicka, Karl Lohner, Nermina Malanovic   +15 more
wiley   +1 more source

Artificially intelligent nursing homes: a scoping review of palliative care interventions. [PDF]

Front Digit Health
Ronan I, Tabirca S, Murphy D, Cornally N, Saab MM, Crowley P.   +5 more
europepmc   +1 more source

Possibilities and limitations of computer assisted chiral HPLC method development for ozanimod on polysaccharide based chiral stationary phases. [PDF]

Sci Rep
Ferencz E, Szabó ZI, Zöldhegyi A, Dombi G, Molnár G, Dobó M, Varga E, Molnár I, Tóth G.   +8 more
europepmc   +1 more source

Kinetic and Mechanistic Investigation of Cobalt Oxide Hydroxide Thin Films by Square‐Wave Voltammetry and Multi‐Frequency Electrochemical Faradaic Spectroscopy

ChemElectroChem, EarlyView.
The mechanism of the cobalt oxide‐hydroxide redox system is elucidated with square‐wave voltammetry and cyclic voltammetry. Since the cobalt oxide‐hydroxide deposits are films of certain thickness, markers derived from unique features in square‐wave voltammetry are provided to identify thin‐film behavior and characterize the cobalt oxide‐hydroxide ...
Franz Glaubitz, Erik Lindemann, Valentin Mirceski, Uwe Schröder   +3 more
wiley   +1 more source

Assessing the Influence of Illumination on Ion Conductivity in Perovskite Solar Cells. [PDF]

J Phys Chem Lett
Schiller A, Jenatsch S, Blülle B, Torre Cachafeiro MA, Ebadi F, Kabir N, Othman M, Wolff CM, Hessler-Wyser A, Ballif C, Tress W, Ruhstaller B.   +11 more
europepmc   +1 more source

Novel quinazolinones active against multidrug‐resistant Mycobacterium tuberculosis: synthesis, antimicrobial evaluation and in silico exploration of PonA1 as a potential target

ChemMedChem, Accepted Article.
Quinazolinone derivatives have emerged as promising scaffolds in antimicrobial drug discovery. This work focuses on the design, synthesis, and evaluation of novel quinazolinone‐based compounds and predicts their potential to interact with mycobacterial penicillin‐binding proteins (PBPs).
MAREK KERDA, Daria Nawrot, Petr Slechta, Mirek Domanský, Asal Askari, Hanieh Kamangar, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Ingrid Hlbočanová, Miloslav Macháček, Matteo Mori, Fiorella Meneghetti, Martin Doležal, Jan Zitko, Ghada Bouz   +15 more
wiley   +1 more source

Blood-based biomarkers and plasma Aβ assays in the differential diagnosis of Alzheimer's disease and behavioral-variant frontotemporal dementia. [PDF]

Alzheimers Res Ther
Mohaupt P, Kindermans J, Vialaret J, Anderl-Straub S, Werner L, Lehmann S, Hirtz C, Otto M, Oeckl P.   +8 more
europepmc   +1 more source