Results 261 to 270 of about 2,016,645 (349)

A Wearable Electrochemical Biosensor for Salivary Detection of Periodontal Inflammation Biomarkers: Molecularly Imprinted Polymer Sensor with Deep Learning Integration

Advanced Science, EarlyView.
A wearable electrochemical biosensor integrated into a smart mouthguard enables the non‐invasive detection of salivary MMP‐8 for early monitoring of periodontal inflammation. Featuring a molecularly imprinted polymer‐based sensing layer, the platform offers high cytokine selectivity and impedance‐driven sensitivity. Combining wireless connectivity with
Sangheon Jeon, Sung Hyun Kim, Gyeonghwa Heo, Hye Jin Heo, Seon Yeong Chae, Young Woo Kwon, Shin‐Kyu Lee, Dong‐Wook Han, Hyun‐Joo Kim, Yun Hak Kim, Suck Won Hong   +10 more
wiley   +1 more source

Validation and Acceptability of the Mobile App Version of the Control of Allergic Rhinitis and Asthma Test for Children (CARATKids): Cross-Sectional Study. [PDF]

JMIR Pediatr Parent
Abreu da Mata D, Pais-Cunha I, Ferraz SC, da Rocha Couto D, Ferraz C, Silva S, Valente JC, Vieira-Marques P, A Fonseca J, Azevedo I, Jácome C.   +10 more
europepmc   +1 more source

ARL3 Enhances ERα Stability via USP10 Deubiquitination to Promote Endocrine Resistance and Drive Mitochondrial Metabolic Reprogramming in HR+ Breast Cancer

Advanced Science, EarlyView.
This study identifies ADP‐ribosylation factor‐like protein 3 (ARL3) as a novel chaperone that stabilizes estrogen receptor α (ERα) in breast cancer. ARL3 promotes tumor growth by recruiting USP10 to remove ubiquitin chains from ERα, preventing its degradation.
Han Li, Yang Liu, Zehao Cai, Kang Li, Shun Gao, Ailin Lan, Dan Shu, Kuan He, Xin Liu, Yang Peng, Shipeng Guo, Haochen Yu, Aishun Jin, Meiying Shen, Shengchun Liu   +14 more
wiley   +1 more source

Characterisation and analysis of mRNA critical quality attributes using liquid chromatography based methods.

J Chromatogr A
Webb ALJ, Welbourne EN, Evans CA, Dickman MJ.   +3 more
europepmc   +1 more source

Effect of mobile phone addiction on hand disorder, eye health, fatıgue and cognitive failures. [PDF]

BMC Public Health
Özalp M.
europepmc   +1 more source

Procyanidin B3 and Its Derivatives Alleviate Neuronal Injury by Targeting G3BP1 for Ischemic Stroke Therapy

Advanced Science, EarlyView.
Ischemic stroke is a serious disease with high rates of mortality and disability, but there is a lack of novel therapeutic targets and agents for it. Now it is shown that Ras GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1) has the potential to serve as a therapeutic target for ischemic stroke.
Heyanhao Zhang, Yuyu Zhang, Yibo Chen, Wen Zhong, Subei Tan, Jinghuan Wang, Huanren Yan, Ning Yan, Mengjia Lin, Xinhua Liu, Jun Chang   +10 more
wiley   +1 more source

K29‐Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response

Advanced Science, EarlyView.
Under endoplasmic reticulum stress, cells activate the unfolded protein response (UPR). During the UPR, the cohesin complex at the promoter of cell proliferation‐related genes undergoes K29‐linked ubiquitination, recruiting the cohesin release factor WAPL to release cohesin, leading to transcriptional downregulation and inhibition of cell growth ...
Qiushuang Zhang, Xucong Teng, Yicong Dai, Yuncong Wu, Hongwei Hou, Jinghong Li   +5 more
wiley   +1 more source

Hypoxia‐Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis

Advanced Science, EarlyView.
Hypoxia triggers lactylation of PRMT1 at K134/K145, enhancing its methyltransferase activity to asymmetrically dimethylate vimentin R64. This post‐translational cascade promotes vimentin filament assembly, cytoskeletal remodeling, and tumor metastasis, with PRMT1 inhibition (MS023) reducing metastatic colonization.
Jia Zhou, Shuying Qiu, Xia Yang, Yan Wu, Xinxia Yao, Hangqi Hu, Jingfeng Luo, Chandra Sugiarto Wijaya, Lingfeng Ma, Xiaojun Long, Lingna Xu, Jinquan Liu, Chaoqun Wang, Yibin Pan, Xiaona Chen, Hongchuan Jin, Xian Wang   +16 more
wiley   +1 more source

Nanopore-Aware Embedded Detection for Mobile DNA Sequencing: A Viterbi-HMM Design Versus Deep Learning Approaches. [PDF]

Biosensors (Basel)
Hammad K, Wu Z, Ghafar-Zadeh E, Magierowski S.   +3 more
europepmc   +1 more source

From Knitting Technology to Robotics: Untethered Thermally Actuated Textile Exoskeleton for Dexterity Applications

Advanced Science, EarlyView.
A textile‐based exoskeleton glove with integrated thermally driven actuators achieves rapid, low‐power response for dexterous motion. Utilizing advanced knitting methods, embedded heaters, and hybrid yarn sensors, the glove bends in a segmented fashion under 12 s at only 10.8 W and 48 °C.
Ibrahim Adel Khamis Ahmed, Munire Sibel Cetin, Kadir Ozlem, Asli Tuncay Atalay, Gökhan Ince, Ozgur Atalay   +5 more
wiley   +1 more source