Results 31 to 40 of about 101,253 (265)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

KIT MOMA: A Mobile Machines Dataset

open access: yesCoRR, 2020
Mobile machines typically working in a closed site, have a high potential to utilize autonomous driving technology. However, vigorously thriving development and innovation are happening mostly in the area of passenger cars. In contrast, although there are also many research pieces about autonomous driving or working in mobile machines, a consensus ...
Yusheng Xiang   +6 more
openaire   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Dynamics of Multibody Systems of Machines under Changing States of Frictional Components and Directions of Power Flows

open access: yesМеханика машин, механизмов и материалов, 2014
Features for creation of mathematical models for dynamic calculations of multibody systems on their transitional modes with changing the system states and the direction of power flows are considered.
V.B. Algin
doaj  

Evolution of machine intelligence for mobile robot.

open access: yesJournal of the Robotics Society of Japan, 1988
Active research and development is carried out for various mobile robots or robotic vehicles. This paper tries to find a new principle of the evolution of machine intelligence for robotic vehicles. The machine intelligence of robotic vehicles is the integrated ability composed of sensors, actuators, and computers, which produces the travel versatility ...
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Results of National R&D in Mechanics of Mobile Machines under a View to the Congress “Mechanics - 2013”

open access: yesМеханика машин, механизмов и материалов, 2014
Main results of national R & D which correspond to world standards and were presented on the congress "Mechanics - 2013" are described.
A.A. Djuzhev, V.B. Algin
doaj  

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Optimization of elastic elements of a damping devices for cylindrical hinges in crane-manipulating installations of mobile machines [PDF]

open access: yesНаучно-технический вестник Брянского государственного университета, 2016
The article considers the problems of designing an original damping devices worn for cylindrical hinges in crane-manipulating installations of mobile machines.
Lagerev I.A.
doaj  

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