Results 61 to 70 of about 148,372 (267)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Enhancing Wireless Network Efficiency with the Techniques of Dynamic Distributed Load Balancing: A Distance-Based Approach

Sensors
The unique combination of the high data rates, ultra-low latency, and massive machine communication capability of 5G networks has facilitated the development of a diverse range of applications distinguished by varying connectivity needs.
Mustafa Mohammed Hasan Alkalsh, Adrian Kliks   +1 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Coherence and fidelity aware routing in quantum networks

Scientific Reports
In quantum networks, routing mechanisms designed to deliver successfully multiple simultaneous requests to the destination under limited channel capacity should simultaneously consider resource usage optimization, entanglement-generation performance, and
Hilal Sultan Duranoglu Tunc, Joy Halder, Azita Hajizade, Andreas Voigt, Bassem Arar, Riccardo Bassoli, Gerhard P. Fettweis, Frank H. P. Fitzek   +7 more
doaj   +1 more source

Towards Energy-Efficient Underlaid Device-to-Device Communications: A Joint Resource Management Approach

IEEE Access, 2019
With increasing demands of green wireless communications, energy-efficient device-to-device (D2D) communications have attracted increasing attention. However, with resource sharing in an underlying manner, the system performance may be greatly degraded ...
Rui Zhang, Chuhan Qi, Yongzhao Li, Yuhan Ruan, Cheng-Xiang Wang, Hailin Zhang   +5 more
doaj   +1 more source

Performance Comparison of QoS Deployment Strategies for Cellular Network Services

IEEE Access, 2020
Differentiated quality-of-Service (QoS) techniques are widely used to distinguish between different service classes and prioritize service needs in mobile networks.
Engin Zeydan, Josep Mangues-Bafalluy, Omer Dedeoglu, Yekta Turk   +3 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Simplified Methodology of Electromagnetic Field Measurements in the Vicinity of 5G Massive MIMO Base Station for Environmental Exposure Assessment

IEEE Access
The development of wireless systems technologies consists, on the one hand, in new methods of generating a radio signal and, on the other hand, in optimizing the transmission of this signal, for instance, by using modern multiantenna technology.
Pawel Bienkowski, Bartlomiej Zubrzak, Przemyslaw Sobkiewicz, Kamil Bechta, Marcin Rybakowski   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Network Integrity in Mobile Robotic Networks [PDF]

IEEE Transactions on Automatic Control, 2013
Most coordinated tasks performed by teams of mobile robots require reliable communications between team members. Therefore, task accomplishment requires that robots navigate their environment with their collective movement restricted to formations that guarantee integrity of the communication network.
Michael M. Zavlanos, Alejandro Ribeiro, George J. Pappas   +2 more
openaire   +1 more source