Results 81 to 90 of about 364,278 (313)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Participants Ranking Algorithm for Crowdsensing in Mobile Communication
EAI Endorsed Transactions on Scalable Information Systems, 2018 As mobile technology is becoming more advance, the uses of this technology is increasing day by day. The mobile phone is used by everyone and it became the necessity of life. Today, smart devices are flooding the internet with data that are everywhere and
Tariq Ali +5 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Indoor localization of a mobile robot using sensor fusion : a thesis presented in partial fulfilment of the requirements for the degree of Master of Engineering in Mechatronics with Honours at Massey University, Wellington, New Zealand [PDF]
, 2011 Reliable indoor navigation of mobile robots has been a popular research topic in recent years. GPS systems used for outdoor mobile robot navigation can not be used indoor (warehouse, hospital or other buildings) because it requires an unobstructed view ...
Zhou, Jason
core
Coverage Control for Mobile Sensing Networks
IEEE Transactions on Robotics and Automation, 2003 13 pages; double column; 6 figures; submitted to IEEE Transactions on Robotics and ...
Cortes, J. +3 more
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Movement-Efficient Sensor Deployment in Wireless Sensor Networks With Limited Communication Range. [PDF]
, 2018 We study a mobile wireless sensor network (MWSN) consisting of multiple mobile sensors or robots. Three key factors in MWSNs, sensing quality, energy consumption, and connectivity, have attracted plenty of attention, but the interaction of these factors ...
Guo, Jun, Jafarkhani, Hamid
core +2 more sources
Towards Around-Device Interaction using Corneal Imaging
, 2017 Around-device interaction techniques aim at extending the input space using various sensing modalities on mobile and wearable devices. In this paper, we present our work towards extending the input area of mobile devices using front-facing device ...
Grubert, Jens, Schneider, Daniel
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source