Results 81 to 90 of about 2,399,237 (291)

Sensing the Common: On the Mobilities and Makings of Sense

, 2023
AbstractHow should we make sense of our current situation, global and local? What could such a making of sense imply? What, indeed, should we make of the notion of sense in this regard? In this chapter, in the company of Merleau-Ponty, Barad, Ingold and others, the modalities of sense are explored and deployed in interrelation with lived experiences of
openaire   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Mobile crowd sensing management with the ParticipAct living lab [PDF]

, 2017
The widespread availability of smartphones have enabled the blossom of Mobile Crowd Sensing (MCS) projects, whose goal is to involve users in participatory tasks aimed at building large real-world datasets.
Ianniello, Raffaele, Corradi, Antonio, Foschini, Luca, Bellavista, Paolo, CHESSA, STEFANO, GIROLAMI, MICHELE, Girolami M, Foschini L, Bellavista P, Corradi A, Ianniello R, Chessa S   +11 more
core   +1 more source

Energy Efficient Social Routing Framework for Mobile Social Sensing Networks

Tsinghua Science and Technology, 2016
Mobile social sensing network is one kind of emerging networks in which sensing tasks are performed by mobile users and sensing data are shared and collected by leveraging the intermittent inter-contacts among mobile users.
Fan Li, Chenfei Tian, Ting Li, Yu Wang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Participants Ranking Algorithm for Crowdsensing in Mobile Communication

EAI Endorsed Transactions on Scalable Information Systems, 2018
As mobile technology is becoming more advance, the uses of this technology is increasing day by day. The mobile phone is used by everyone and it became the necessity of life. Today, smart devices are flooding the internet with data that are everywhere and
Tariq Ali, Javeria Noureen, Umar Draz, Ahmad Shaf, Sana Yasin, Muhammad Ayaz   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Mars: a personalised mobile activity recognition system [PDF]

, 2012
Mobile activity recognition focuses on inferring the current activities of a mobile user by leveraging the sensory data that is available on today’s smart phones.
Krishnaswamy, S., Shonali Krishnaswamy, Bártolo Gomes, Joao Paulo, Mohamed Medhat Gaber, Gaber, M., Gomes, J., Sousa, P., Pedro A.C. Sousa, Menasalvas, E., Joao B'rtolo Gomes, Krishnaswamy, Shonali, Ernestina Menasalvas, Gaber, Mohamed M., Sousa, Pedro, Menasalvas Ruiz, Ernestina   +14 more
core   +1 more source