Results 111 to 120 of about 118,036 (253)

Négocier les futurs d’un territoire nucléaire : le cas de La Hague

open access: yesEchoGéo
This article examines the negotiations over the future of an area dominated by a nuclear plant. The future of the area is also replayed by the plan to extend the plant as part of the nuclear storage pool project, which stabilises the area's industrial ...
Youenn Gourain, Christine Fassert
doaj   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang   +11 more
wiley   +1 more source

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

open access: yesAdvanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel   +10 more
wiley   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

open access: yesAdvanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia   +10 more
wiley   +1 more source

Constitutional Mobilisation in China

open access: yes, 2017
This paper examines recent constitutional mobilisation in China, embodied in the weiquan (right defence) movement, Charter 08 and the 2013 constitutionalism debate. It contrasts Chinese and Vietnamese experience of constitutional mobilisation. This paper
Bui Ngoc Son
core   +1 more source

Experiences of volunteers: A volunteer-led community strategy for lung cancer awareness and mobilisation in KwaZulu-Natal

open access: yesAfrican Journal of Primary Health Care & Family Medicine
Background: Community health awareness is essential in ensuring communities are well-informed about different health-related challenges and promoting health-seeking behaviour.
Sthabile W. Mtolo   +2 more
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Past National Mobilisation Insights: Supply Chains, the People and Supporting Great Power Allies (Working paper)

open access: yes, 2020
In this multi-author edition of the Centre of Gravity series, four leading thinkers explore issues and opportunities of mobilisation in Australia. Peter Layton explores recent history to argue that Australian defence strategies, and accordingly the ADF ...
Layton, Peter
core  

Lobbying associatif : l’exemple de l’autisme

open access: yesRevue Médecine et Philosophie, 2019
Comment le système associatif contribue-t-il à façonner les représentations et les politiques publiques en matière d’autisme ? Cette question renvoie au rôle plus général des mouvements sociaux.
Brigitte Chamak
doaj  

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert   +8 more
wiley   +1 more source

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