Results 41 to 50 of about 52,466 (256)

STRATÉGIES DE MOBILISATION DES RECETTES PARAFISCALES : CAS DE LA DIRECTION GÉNÉRALE DES RECETTES ADMINISTRATIVES, JUDICIAIRES, DOMANIALES ET DE PARTICIPATIONS (DGRAD) [PDF]

open access: yesCahiers Africains des Droits de l’Homme et de la Démocratie ainsi que du Développement Durable, 2023
Dans cet article, la réflexion est articulée autour de la fiscalité comme outil de développement de la République Démocratique du Congo. En effet, dans le souci de faire un contrôle judicieux dans le processus de recouvrement de recettes non fiscales ...
Philippe NDONGO AHUAZO   +2 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Activismo y Prácticas Digitales en la Construcción de una Esfera LGTB en España

open access: yesDados: Revista de Ciências Sociais
RESUMEN A partir de una interrogación antropológica sobre las “comunidades” y la construcción de una “esfera pública”, este artículo aborda las estrategias digitales que sirven para dar forma a lo que podría denominarse como la esfera LGTB española ...
Begonya Enguix Grau
doaj   +1 more source

La culture juridique des hommes d’Église en Anjou et dans le Maine (XIVe – début XVIe siècles) - The Legal Culture of the Clergy in Anjou and Maine (from the 14th to the Early 16th Centuries) [PDF]

open access: yesBelvedere Meridionale, 2015
Dealing with the legal culture of the clergymen in the late Middle Ages, this study aims to comprehend the coincidence between the spread of a particular type of intellectual training and the consciousness that a social group could have to build its own ...
MATZ, Jean-Michel
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

War, industrial mobilisation and society in Northern Ireland, 1939-1945 [PDF]

open access: yes, 2007
Archive-based regional studies can contribute much that is new to the economic, political and social history of the Second World War. This paper considers the process of industrial mobilisation in Northern Ireland, a politically divided region which was ...
Ollerenshaw, Philip
core   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Relevance of Tibial Fixation during Tibiotarsal Joint Traction: Descriptive Cross-Sectional Study

open access: yesJournal of Functional Morphology and Kinesiology
Background: The effect of tibial fixation on the movement of the talus during the tibiotarsal axial traction technique (TATT) is unknown. The aim was to evaluate the effect on the tibiotarsus when applying three different intensities of TATT force with ...
Carlos López-de-Celis   +6 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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