Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Although train modeling research is vast, most available simulation tools are confined to city- or trip-scale analysis, primarily offering micro-level simulations of network segments.
Ahmed S. Aredah +2 more
doaj +1 more source
Experimental Study on Pure Ammonia as a Single Fuel in a Range-Extended Electric Vehicle
Ammonia can significantly reduce carbon emissions when used in internal combustion engines. However, pure ammonia is considered difficult to ignite and has a slow flame propagation speed, which makes its application challenging.
Qiyang Sun +7 more
doaj +1 more source
A Large Anisotropic Enhancement of the Charge Carrier Mobility of Flexible Organic Transistors with Strain: A Hall Effect and Raman Study [PDF]
Hyun Ho Choi +8 more
openalex +1 more source
Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker +9 more
wiley +1 more source
Are Crowdsourced Datasets Suitable for Specialized Routing Services? Case Study of OpenStreetMap for Routing of People with Limited Mobility [PDF]
Amin Mobasheri +3 more
openalex +1 more source
Mobility and Mobility Measures
We examine whether mobility measures appropriately represent changes in individual status, like income or ranks. We suggest three elementary principles for mobility comparisons and show that many commonly used indices violate one or more of them. These principles are used to characterise two classes of measures that have a natural interpretation in ...
Cowell, Frank A., Flachaire, Emmanuel
openaire +2 more sources
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
Rethinking Vehicle Architecture Through Softwarization and Servitization
The automotive industry is undergoing a foundational transformation driven by software-defined vehicles (SDVs), where software not only orchestrates vehicle functionality but also redefines the value proposition through servitization, making services a ...
Alaa Khamis, Partha Goswami
doaj +1 more source
Physics-Based Deformable Tire–Soil Interaction Model for Off-Road Mobility Simulation and Experimental Validation [PDF]
Hiroki Yamashita +3 more
openalex +1 more source

