Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Mapping AI ethics narratives: evidence from Twitter discourse between 2015 and 2022
The ethical issues that arise in the development of AI technologies are closely linked to public engagement. Although Twitter, as an online public sphere, provides a platform for exploring AI ethics discourse, it is difficult for current research to ...
Mengyi Wei +5 more
doaj +1 more source
Geo-Spotting: Mining Online Location-based Services for Optimal Retail Store Placement
The problem of identifying the optimal location for a new retail store has been the focus of past research, especially in the field of land economy, due to its importance in the success of a business.
Karamshuk, Dmytro +4 more
core +1 more source
Stochastic dynamic vehicle routing in the light of prescriptive analytics: A review
Stochastic dynamic vehicle routing problems have become an essential part of logistics and mobility services. In such problems, a sequence of vehicle routing decisions has to be made in reaction and anticipation of newly revealed stochastic information ...
Ninja Soeffker, M. Ulmer, D. Mattfeld
semanticscholar +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Unveiling public perception of AI ethics: an exploration on Wikipedia data
Artificial Intelligence (AI) technologies have exposed more and more ethical issues while providing services to people. It is challenging for people to realize the occurrence of AI ethical issues in most cases.
Mengyi Wei +5 more
doaj +1 more source
MOBILITY ATLAS BOOKLET: AN URBAN DASHBOARD DESIGN AND IMPLEMENTATION [PDF]
The new data sources give the possibility to answer analytically the questions that arise from mobility manager. The process of transforming raw data into knowledge is very complex, and it is necessary to provide metaphors of visualizations that are ...
L. Gabrielli +4 more
doaj +1 more source
Mobility Analytics and COVID-19 in Greece
To appear in: "The Science behind the COVID Pandemic and Healthcare Technology Solutions", pp.
Georgiou, Harris +2 more
openaire +1 more source
Enabling actionable analytics for mobile devices: performance issues of distributed analytics on Hadoop mobile clusters [PDF]
Significant innovations in mobile technologies are enabling mobile users to make real-time actionable decisions based on balancing opportunities and risks to take coordinated actions with other users in their workplace. This requires a new distributed analytic framework that collects relevant information from internal and external sources, performs ...
Lee, Seungbae +2 more
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

