Results 251 to 260 of about 422,750 (312)

Association Between Genetic Ancestry and Multiple Sclerosis Severity

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to determine whether genetic ancestry is associated with differences in the clinical course of multiple sclerosis (MS). Methods Participants with MS living in the United Kingdom >18 years old were recruited from 2021 to 2025 and genotyped from saliva using a commercial array. Genetic ancestry was inferred using
Benjamin M. Jacobs   +32 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

Enhanced recovery after surgery for cesarean delivery: a systematic review and meta-analysis of randomized trials with trial sequential analysis. [PDF]

open access: yesBraz J Anesthesiol
de Oliveira TTC   +9 more
europepmc   +1 more source

Mechanical Thrombectomy Versus Medical Management for Large Ischemic Core Stroke Identified before Inter‐Hospital Transfer: A Post Hoc Analysis of the LASTE Trial

open access: yesAnnals of Neurology, EarlyView.
Objective This study assessed the efficacy of thrombectomy in acute ischemic stroke because of large‐vessel occlusion (AIS‐LVO) initially admitted to primary stroke centers (PSC) and subsequently transferred to a comprehensive stroke center (CSC), with a large ischemic core identified before transfer.
Pierre Seners   +258 more
wiley   +1 more source

Alkoxyethyl Acetate Electrolytes for High‐Voltage Lithium Metal Batteries

open access: yesAngewandte Chemie, EarlyView.
We designed a fluorinated alkoxyethyl acetate solvent for high‐voltage Li‖NMC811 batteries. Introducing a carbonyl group disrupts symmetric bidentate solvation, while terminal fluorination enhances high‐voltage stability and reversible Li plating/stripping. The tailored solvation promotes a robust cathode electrolyte interphase, substantially extending
Xinlin Li   +11 more
wiley   +2 more sources

Prognostic value of day 10 mobilization status for ambulation at hospital discharge in critically ill patients: a historical cohort study in Japan. [PDF]

open access: yesAcute Crit Care
Watanabe T   +11 more
europepmc   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi   +6 more
wiley   +1 more source

"CARING in Action": A Knowledge Mobilization Project on Co-Creating Evidence-Based Communication Training in Chronic Pain Care for Healthcare Professionals. [PDF]

open access: yesCan J Pain
Taccardi D   +8 more
europepmc   +1 more source

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