Results 51 to 60 of about 242,935 (267)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Mobility of Plasmids [PDF]

Microbiology and Molecular Biology Reviews, 2010
SUMMARYPlasmids are key vectors of horizontal gene transfer and essential genetic engineering tools. They code for genes involved in many aspects of microbial biology, including detoxication, virulence, ecological interactions, and antibiotic resistance.
Smillie, C., Garcillan-Barcia, M. P., Francia, M. V., Rocha, Eduardo, de La Cruz, F.   +4 more
openaire   +4 more sources

COMPARATIVE ANALYSIS OF LOW-COST CONSUMER-GRADE AND COMMERCIAL-GRADE DRONES FOR LAND SURVEYING APPLICATIONS [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
This study investigates the feasibility of using low-cost consumer drones, specifically the DJI Mini 2, for land surveys compared to commercial-grade drones like the DJI Phantom 4 Pro V2. The research, conducted within the University of the Philippines -
P. C. Barbosa, D. C. Fargas Jr., D. C. Fargas Jr., G. A. M. Narciso   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Mobilities and peace [PDF]

Globalizations, 2019
This article considers how an increasingly visible set of mobilities has implications for how peace and conflict are imagined and responded to. We are particularly interested in how these mobilities take form in everyday actions and shape new forms of peace and challenge existing ones.
Richmond, Oliver P., Mac Ginty, Roger
openaire   +4 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Activism – Radicalization – Protest: An Introduction to a Special Section [PDF]

Social Psychological Bulletin, 2018
Collective action is a topic that is highly relevant to the socio-political dynamics of the contemporary world. Six papers collected in the special section address different aspects of collective action.
Katarzyna Jasko, Tomasz Besta
doaj   +3 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Assessing soil loss using GIS based RUSLE methodology. Case of the Bou Namoussa watershed – North-East of Algeria

Journal of Water and Land Development, 2018
This study aims to estimating annual soil erosion rate and its spatial distribution in the Bou Namoussa water-shed located in the North-East of Algeria by applying the revised universal soil loss equation (RUSLE) within a Geographical Information System ...
Bouhadeb Chemss Eddine, Menani Mohamed Redha, Bouguerra Hamza, Derdous Oussama   +3 more
doaj   +1 more source