Results 31 to 40 of about 297,336 (298)
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2020 A new set of modals is appearing in contemporary English. The epistemic modals with perfect have are forming a new class including mighta, coulda, woulda, shoulda, and musta, when they are used with an additional have and without a (present) perfect ...
Elly van Gelderen
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The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Analysis, 2017 [Extract] In this article the term ‘modality’, when unmodified, will refer to metaphysical modality. Metaphysical modality is what is expressed by ‘possible’ and variants such as ‘possibly’, as well as ‘it could have been the case that…’ and variants, when these are used in the broadest objective sense.
Strohminger, Margot, Yli-Vakkuri, Juhani
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Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
GFFNet: Global Feature Fusion Network for Semantic Segmentation of Large-Scale Remote Sensing Images
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingSemantic segmentation plays a pivotal role in interpreting high-resolution remote sensing images (RSIs), where contextual information is essential for achieving accurate segmentation.
Yong Cao +3 more
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Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
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Affective Computing: Recent Advances, Challenges, and Future Trends
Intelligent ComputingAffective computing is a rapidly growing multidisciplinary field that encompasses computer science, engineering, psychology, neuroscience, and other related disciplines.
Guanxiong Pei +5 more
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FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
The Implementation of Debate Technique to Enhance the Students’ Speaking Skill
English Education Journal: Jurnal Pengembangan Pendidikan dan Pengembangan Pengajaran Bahasa, 2019 The objective of this research was to improve the quality of teaching and learning speaking by using debate technique at the tenth grade students of SMAN Modal Bangsa, Aceh. The academic year was 2017/2018.
Michael Tianame +2 more
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