Results 61 to 70 of about 84,248 (219)

Modal Testing and Analysis of High-rise Laminated Timber Building

open access: yesBioResources
To enhance the design and research work on dynamic characteristics of high-rise laminated timber buildings, this paper carried out a modal analysis study on one of the largest laminated timber buildings in China.
Qiyun Xu   +5 more
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Negotiating Institutional Hierarchy: Power, Politeness, and Meaning Construction in English-to-Chinese Courtroom Translation

open access: yesSAGE Open
This corpus-based study investigates the translation of modality from English to Chinese in the high-stakes context of the International Military Tribunal for the Far East (IMTFE). Grounded in Systemic Functional Linguistics (SFL), the analysis employs a
Shuangjiao Wu, Mansour Amini, Yiqiu Wang
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Flexible Gumbel Distribution: A New Model for Inference about the Mode

open access: yesStats
A new unimodal distribution family indexed via the mode and three other parameters is derived from a mixture of a Gumbel distribution for the maximum and a Gumbel distribution for the minimum.
Qingyang Liu   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Spectral-Domain Measurements of Birefringence and Sensing Characteristics of a Side-Hole Microstructured Fiber

open access: yesSensors, 2013
We experimentally characterized a birefringent side-hole microstructured fiber in the visible wavelength region. The spectral dependence of the group and phase modal birefringence was measured using the methods of spectral interferometry. The phase modal
Waclaw Urbańczyk   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Modal properties of the flexural vibrating package of rods linked by spacer grids

open access: yesApplied and Computational Mechanics, 2011
The paper deals with the modelling and modal analysis of the large package of identical parallel rods linked by transverse springs (spacer grids) placed on several level spacings.
Zeman V., Hlaváč Z.
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy