Results 41 to 50 of about 1,652 (233)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Trinitarian Thought in the Early Modern Era [PDF]
, 2011 This article explores Catholic and Protestant Trinitarian theology from 1550 to 1770. It discusses various issues, from the mystical visions of Ignatius of Loyola to the Augustinian approach of Jonathan Edwards.
Lehner, Ulrich
core +1 more source
Modals and Modality in English
Miscelánea: A Journal of English and American Studies, 1995 Modality as a linguistic notion has a clear expression in English through the use of different modal verbs. In this respect, we can approach this fact from both a diachronic and a synchronic perspective. In the development of modals in time, it is interesting to consider Bernd Heine's account, for whom modals' development should be considered within a ...
openaire +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai +4 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Ignoring God Triune? The Doctrine of the Trinity in Dutch Theology [PDF]
, 2009 Contains fulltext : 82094.pdf (publisher's version ) (Closed ...
Brink, G. van den, Erp, Stephan van
core +4 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Cognitive Science, 1978 This paper describes a semantics for modal terms such as can and may that is intended to model the mental representation of their meaning. The basic assumption of the theory is that the evaluation of a modal assertion involves an attempted mental construction of a specified alternative to a given situation rather than the separate evaluation of each ...
openaire +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source