Results 81 to 90 of about 1,478,961 (356)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

HeMIS: Hetero-Modal Image Segmentation

open access: yes, 2016
We introduce a deep learning image segmentation framework that is extremely robust to missing imaging modalities. Instead of attempting to impute or synthesize missing data, the proposed approach learns, for each modality, an embedding of the input image
B Menze   +10 more
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Robust Latent Representations via Cross-Modal Translation and Alignment [PDF]

open access: yesICASSP 2021, 2020
Multi-modal learning relates information across observation modalities of the same physical phenomenon to leverage complementary information. Most multi-modal machine learning methods require that all the modalities used for training are also available for testing.
arxiv  

Exploring Modality-shared Appearance Features and Modality-invariant Relation Features for Cross-modality Person Re-Identification [PDF]

open access: yesarXiv, 2021
Most existing cross-modality person re-identification works rely on discriminative modality-shared features for reducing cross-modality variations and intra-modality variations. Despite some initial success, such modality-shared appearance features cannot capture enough modality-invariant discriminative information due to a massive discrepancy between ...
arxiv  

Modalitas Calon Bupati Dalam Pemilihan Umum Kepala Daerah Tahun 2015

open access: yesJournal of Governance and Public Policy, 2017
In the history of political contestation in South Sulawesi as the election, there has never been a woman who has won an election. Moreover, the female candidate is a newcomer in the constituency, while his political opponents in the election are the ...
Tawakkal Baharuddin, Titin Purwaningsih
doaj   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Novel Retinal Imaging Technologies [PDF]

open access: yes, 2017
Newly-developed imaging techniques show extensive promise and potential to improve early detection, accurate diagnosis, and management of retinal diseases.
Li Y, Xia X, Paulus YM
core   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Relational Modality

open access: yesJournal of Logic, Language and Information, 2008
Saul Kripke's thesis that ordinary proper names are rigid designators is supported by widely shared intuitions about the occurrence of names in ordinary modal contexts. By those intuitions names are scopeless with respect to the modal expressions. That is, sentences in a pair like Aristotle might have been fond of dogs Concerning Aristotle, it is ...
Pagin, Peter, Glüer, Kathrin
openaire   +4 more sources

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