Results 111 to 120 of about 145,627 (290)

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Positive Emotion Recognition—A Survey of Computational Models

IEEE Access
In this paper, we provide a systematic survey of works on positive emotion recognition and detection. We queried major research paper databases for 12 different emotional states: admiration, amusement, awe, compassion, contentment, elation, enthusiasm ...
Irem Arici, Radoslaw Niewiadomski
doaj   +1 more source

Intelligence methods of multi-modal information fusion in human-computer interaction [PDF]

, 2018
Minghao Yang, Jianhua Tao
openalex   +1 more source

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

On the Benefit of FMG and EMG Sensor Fusion for Gesture Recognition Using Cross-Subject Validation

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Hand gestures are a natural form of human communication, making gesture recognition a sensible approach for intuitive human-computer interaction. Wearable sensors on the forearm can be used to detect the muscle contractions that generate these gestures ...
Maurice Rohr, Jad Haidamous, Niklas Schafer, Stephan Schaumann, Bastian Latsch, Mario Kupnik, Christoph Hoog Antink   +6 more
doaj   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

Advanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun, Jiachen Lin, Chenyang Xue, Yuyan Wang, Peiru Chen, Yun Wei, Guobin Xu, Anais Sidonia, Chris Nenopoulos, Hossam Tashkandi, Caroline Shen, Allison Wang, Alex Wang, Ke Zhang   +13 more
wiley   +1 more source

Cross-modality fusion with EEG and text for enhanced emotion detection in English writing

Frontiers in Neurorobotics
IntroductionEmotion detection in written text is critical for applications in human-computer interaction, affective computing, and personalized content recommendation. Traditional approaches to emotion detection primarily leverage textual features, using
Jing Wang, Ci Zhang
doaj   +1 more source

Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor‐Stroma Co‐Culture Model

Advanced Healthcare Materials, EarlyView.
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret, Jean‐Baptiste Billeau, Michael H. Weber, Derek H. Rosenzweig, Stephan Reuter   +4 more
wiley   +1 more source

Exploring Central-Peripheral Nervous System Interaction Through Multimodal Biosignals: A Systematic Review

IEEE Access
The interaction between the central nervous system (CNS) and peripheral nervous system (PNS) governs various physiological functions, influences cognitive processes and emotional states. It is necessary to unravel the mechanisms governing the interaction
Sourabh Banik, Himanshu Kumar, Nagarajan Ganapathy, Ramakrishnan Swaminathan   +3 more
doaj   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source