Results 181 to 190 of about 7,479 (241)

Multiplexed ultrasound imaging of gene expression. [PDF]

Nat Methods
Nyström NN, Jin Z, Bennett ME, Zhang R, Swift MB, Shapiro MG.   +5 more
europepmc   +1 more source

Tumor‐Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis

Advanced Science, EarlyView.
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu, Jiajia Zhuo, Xiaoquan Hong, Shihao Rao, Yafang Ye, Dandan Kang, Huifang Peng, Huiqin Zhuo   +7 more
wiley   +1 more source

Integrated Communication and Navigation Measurement Signal Design for LEO Satellites with Side-Tone Modulation. [PDF]

Sensors (Basel)
Li X, Feng Y, Xue L.
europepmc   +1 more source

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

High-speed all-optical neural networks empowered spatiotemporal mode multiplexing. [PDF]

Light Sci Appl
Feng F, Li X, Zhang Z, Gan J, Yuan X.
europepmc   +1 more source

Multimodal Super‐Resolution Imaging of Nitrogen‐Vacancy Centers via High‐Index‐Induced Structured Illumination Microscopy and Optically Detected Magnetic Resonance Spectrometry

Advanced Science, EarlyView.
This work demonstrates a multimodal super‐resolution imaging technique for nitrogen‐vacancy centers by integrating high‐index‐induced structured illumination with optically detected magnetic resonance. By utilizing diamond's high refractive index, the method achieves sub‐100‐nm spatial resolution and enhanced localization. This dual‐modulation strategy
Kyu Ri Choi, Mohammed Zia Jalaludeen, Samuel Begumya, Yan Qiu Du, Dong Hee Park, Bin Chan Joo, Jae Hwan Yoo, Síle Nic Chormaic, Shilong Li, Yeon Ui Lee   +9 more
wiley   +1 more source

Chiral valley edge states based on Dirac mass engineering. [PDF]

Nat Commun
Liu JW, Liu GG, Zhang B, Mo HC, Li R, Li M, Chen XD, Zhang B, Chen WJ, Dong JW.   +9 more
europepmc   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

Structuring light with flows. [PDF]

Nat Commun
Yan W, Yuan Z, Gao Y, Chen Z, Ren ZC, Wang XL, Ding J, Wang HT.   +7 more
europepmc   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source