Results 181 to 190 of about 4,119,438 (303)

Paving the way for rural revitalization: Empirical analysis of the 'Sihao Rural Road Policy' and transport mode choice in Inner Mongolia, China. [PDF]

PLoS One
Bao Y, Wuri G, Shan D, Bao L.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Internet and foreign market entry mode : some evidence from Hong Kong [PDF]

Perspectives on entry mode choice are broad, emphasising different tenets and variables. However, none of them has examined the impact of the Internet, which has emerged since the 1980s. The thesis aims to investigate to what extent differing Internet
Chen, Helen
core  

A systematic review of machine learning classification methodologies for modelling passenger mode choice

Machine Learning (ML) approaches are increasingly being investigated as an alternative to Random Utility Models (RUMs) for modelling passenger mode choice.
Hillel, Tim, Elshafie, Mohammed Z. E. B., Bierlaire, Michel, Jin, Ying   +3 more
core   +1 more source

Oldest old's travel mode choice and new mobility technology acceptance: case in America and China. [PDF]

Front Public Health
Zhang Y, Guan J, D'Ambrosio LA, Miller J, Lee C, Zhang K, Coughlin JF.   +6 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Development of a multifactorial prediction model for commute mode choice in 10 983 Finnish public sector employees: a cross-sectional study. [PDF]

BMJ Open
Makkonen A, Gluschkoff K, Airaksinen J, Halonen JI, Salo P, Ervasti J.   +5 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

NARAL Flyer "Know the Facts: Misinformation in 12th & Delaware"

, 2010
Literature that corrects misspoken facts by anti-choice protestors in the movie 12th ...
NARAL Pro-Choice America
core  

Traffic Safety Perception, Attitude, and Feeder Mode Choice of Metro Commute: Evidence from Shenzhen. [PDF]

Int J Environ Res Public Health, 2020
Guo Y, Yang L, Huang W, Guo Y.
europepmc   +1 more source