Results 211 to 220 of about 7,190,509 (398)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Impacts of Pokémon GO on route and mode choice decisions: exploring the potential for integrating augmented reality, gamification, and social components in mobile apps to influence travel decisions. [PDF]

Transportation (Amst), 2022
Guo Y, Peeta S, Agrawal S, Benedyk I.
europepmc   +1 more source

Logistic imperatives and mode choice

, 2010
In freight transport, mode choice depends heavily on the characteristics of the supply chain. This paper presents how a classic theoretical model of inventory theory can be derived to formulate a theoretical specification of the value of time in freight transport.
openaire   +2 more sources

Car Ownership and Mode of Transport to Work in Ireland [PDF]

Rapid economic and demographic change in Ireland over the last decade, with associated increases in car dependence and congestion, has focused policy on encouraging more sustainable forms of travel.
Anne Nolan, Nicola Commins
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Bridging the attitude-behaviour gap: An explanation of travel mode choice using analytical sociology. [PDF]

PLoS One
Weyer J, Hoffmann S.
europepmc   +1 more source

TRANSPORT MODE CHOICE AMONG OFF-CAMPUS STUDENTS IN A HILLY ENVIRONMENT: THE CASE OF AIZAWL, INDIA

, 2022
Benjamin L. SAITLUANGA, Lal Hmangaihzela
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Paving the way for rural revitalization: Empirical analysis of the 'Sihao Rural Road Policy' and transport mode choice in Inner Mongolia, China. [PDF]

PLoS One
Bao Y, Wuri G, Shan D, Bao L.
europepmc   +1 more source

A Comparative Study on Travel Mode Choice Behavior Considering the Cumulative Prospect Theory

, 2013
김관용, Sangho Choo, kee yeon Hwang
openalex   +1 more source