Results 51 to 60 of about 4,119,438 (303)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modeling market entry mode choice : the case of German firms in China [PDF]
, 2005 Zhao X. Modeling market entry mode choice : the case of German firms in China.
Zhao, Xuemin
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Transport Mode Choice for Disaggregated Mobility Demand Generation
IEEE AccessThe OpenStreetMap Mobility Demand Generator (OMOD) is an open-source tool that creates realistic synthetic mobility demand for any region in Germany. The tool focuses on ease of use and fast prototyping, and requires only OpenStreetMap (OSM) data from ...
Leo Strobel, Marco Pruckner
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Estimation of the willingness to pay for public transport improvements [PDF]
برنامهریزی و بودجهThis research examines people's willingness to pay (WTP) for improvements in public transportation as part of transportation demand management (TDM) policies. Proposed enhancements include reduced in-vehicle congestion, shorter access times for buses and
ReyhanehSadat Shahangian, Neda Ghasemi
doaj
Analysis of school commuting behavior differences based on China family panel studies
Shenzhen Daxue xuebao. Ligong banSchool commuting is a crucial aspect of children's daily routines and family travel. The choice of school travel mode significantly impacts children's safety, convenience, and the optimization of urban transportation systems. Utilizing data from the 2020
HUANG Yue +4 more
doaj +1 more source
Application of Discrete Choice Models for Exploring Traveller’s Behaviour at Egyptian Transport Network [PDF]
Port Said Engineering Research Journal, 2018 Mode choice models generally form a critical part of the analysis of the travel demand of any study area in any country and have played an important role in transport modelling over the last decades.
Ahmed Semeida
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source