Results 181 to 190 of about 256,506 (372)

MTFR2‐Mediated Fission Drives Fatty Acid and Mitochondrial Co‐Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis

Advanced Science, EarlyView.
In the tumor margin of hepatocellular carcinoma (HCC), activated hepatic stellate cells upregulate MTFR2, initiating inhibiting DRP1 degradation and mitochondrial fission. This enhances mitochondrial availability and facilitates FAs synthesis via ACC1. Additionally, fission promotes RAC1‐mediated cytoskeletal remodeling and Miro1‐mediated mitochondrial
La Zhang, Baoyong Zhou, Jun Yang, Cong Ren, Jing Luo, Zhenghang Li, Qiang Liu, Zuotian Huang, Zhongjun Wu, Ning Jiang   +9 more
wiley   +1 more source

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source

Mode division multiplexing using an orbital angular momentum mode sorter and MIMO-DSP over a graded-index few-mode optical fibre. [PDF]

Sci Rep, 2015
Huang H, Milione G, Lavery MP, Xie G, Ren Y, Cao Y, Ahmed N, An Nguyen T, Nolan DA, Li MJ, Tur M, Alfano RR, Willner AE.   +12 more
europepmc   +1 more source

Optical switch compatible with wavelength division multiplexing and mode division multiplexing for photonic networks-on-chip

, 2017
Hao Jia, Ting Zhou, Lei Zhang, Jianfeng Ding, Xin Fu, Lin Yang   +5 more
openalex   +1 more source

Density-matrix formalism for modal coupling and dispersion in mode-division multiplexing communications systems

, 2020
Zhenshan Yang, Xiaoguang Zhang, Bin Zhang, Xia Zhang, Zhentao Zhang, Xiang‐Guo Meng, Chenglin Bai   +6 more
openalex   +1 more source

PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti‐TIGIT Therapy in Microsatellite‐Stable Colorectal Cancer

Advanced Science, EarlyView.
Microsatellite‐stable (MSS) colorectal cancer (CRC) resists immunotherapy. PRMT5 inhibition enhances CPT‐11 sensitivity, inducing a PMS2‐deficient‐like state and cytosolic dsDNA release, which activates the cGAS‐STING pathway to promote anti‐tumor immunity. However, this combination therapy upregulates TIGIT expression on CD8+ T cells, and the addition
Jiang Zhu, Shenao Fu, Xi Zou, Hanjiang Zeng, Guangzu Cui, Yinghui Peng, Diya Tang, Fan Zhang, Hong Shen, Shan Zeng, Ying Han   +10 more
wiley   +1 more source

Natural Crystal Structure for Generating Raman‐Like Orbital Angular Momentum States

Advanced Science, EarlyView.
This work proposes a strategy for symmetry breaking of the degenerate OAM states relying on the natural anisotropy of crystal gain, to select the handedness of the spatial spiral phase front and further tunable Raman‐like OAM states by thermal‐driven, which clarifies the contribution of intrinsic crystal property to the OAM states and opens a new route
Tianxiang Meng, Changsheng Zheng, Yongguang Zhao, Haohai Yu, Huaijin Zhang   +4 more
wiley   +1 more source

Mode-Division-Multiplexing of Multiple Bessel-Gaussian Beams Carrying Orbital-Angular-Momentum for Obstruction-Tolerant Free-Space Optical and Millimetre-Wave Communication Links. [PDF]

Sci Rep, 2016
Ahmed N, Zhao Z, Li L, Huang H, Lavery MP, Liao P, Yan Y, Wang Z, Xie G, Ren Y, Almaiman A, Willner AJ, Ashrafi S, Molisch AF, Tur M, Willner AE.   +15 more
europepmc   +1 more source

Elliptical Core Few Mode Fibers for Multiple-Input Multiple Output-Free Space Division Multiplexing Transmission

, 2017
Francesca Parmigiani, Yongmin Jung, Lars Grüner-Nielsen, T. Geisler, Periklis Petropoulos, David J. Richardson   +5 more
openalex   +2 more sources

Photonic Bayesian Neural Networks: Leveraging Programmable Noise for Robust and Uncertainty‐Aware Computing

Advanced Science, EarlyView.
This work introduces a novel photonic Bayesian neural network architecture that utilizes tunable photonic random number generators to independently control weight distribution parameters, significantly improving robustness, scalability, and accuracy while demonstrating practical applications in multimodal data processing and uncertainty‐aware computing.
Yangyang Zhuge, Zhihao Ren, Zian Xiao, Zixuan Zhang, Xinmiao Liu, Weixin Liu, Siyu Xu, Chong Pei Ho, Nanxi Li, Chengkuo Lee   +9 more
wiley   +1 more source