Results 31 to 40 of about 7,768 (254)

High-Dimensional Modulation for Mode-Division Multiplexing [PDF]

open access: yesOptical Fiber Communication Conference, 2014
We explore high-dimensional modulation for mode-division multiplexed optical fiber communication systems, focusing on optimized 24-D modulation formats in six-mode fiber transmission. Compared with conventional formats, our simulations demonstrate up to 8.7 dB span loss budget improvement for 6 b/s/Hz intra-channel spectral efficiency.
Sercan Ö. Arik   +4 more
openaire   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cylindrical vector beam multiplexer/demultiplexer using off-axis polarization control

open access: yesLight: Science & Applications, 2021
The emergence of cylindrical vector beam (CVB) multiplexing has opened new avenues for high-capacity optical communication. Although several configurations have been developed to couple/separate CVBs, the CVB multiplexer/demultiplexer remains elusive due
Shuqing Chen   +8 more
doaj   +1 more source

2D least-squares mode decomposition for mode division multiplexing

open access: yesOptics Express, 2022
We investigate a fast and accurate technique for mode decomposition in multimode optical fibers. Initial decomposition task of near-field beam patterns is reformulated in terms of a system of linear equations, requires neither machine learning nor iterative routines.
Pavel S. Anisimov   +2 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Сompensator of polarization mode dispersion based on spiral-wound single-mode fiber [PDF]

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2013
A polarization mode dispersion (PMD) compensator for single-mode optical fiber has been designed. Its operation principle is based on the use of artificial difference of phase velocities of the basic ordinary and extraordinary waves in spiral-wound fiber,
Bagachuk D. G.
doaj   +2 more sources

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Silicon-Based-Chip Multiplexing Technologies and Devices

open access: yesDianxin kexue, 2015
As the demands of the data communications increase quickly for the applications of cloud-computing as well as data centers,optical interconnects have been very attractive because of the unique advantages on the aspects of low power consumption,high speed
Daoxin Dai, Jian Wang, Sitao Chen
doaj   +2 more sources

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