Destinacijski menadžment - modeli i tehnike
, 2008 Knjiga se bavi destinacijskim menadžmentom, njegovim tehnikama i modelima. Autor je pokušao da se popuni praznina koja se odnosi na destinacijski menadžment u smislu njegovog pojmovnog određenja, javnih funkcija u destinaciji te modela i tehnika kao i organizacijskih struktura kroz koje bi se destinacijski menadžment trebao institucionalizirati.
openaire +2 more sources
Loading Rate and Temperature Interaction Effects on the Mode I Fracture Response of a Ductile Polyurethane Adhesive Used in the Automotive Industry. [PDF]
Materials (Basel), 2022 Perez M +5 more
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Evaluation of Mode-I Fracture Toughness of Asphalt Mixtures with Symmetric Geometry Specimen at Intermediate Temperature. [PDF]
Materials (Basel), 2022 Pérez-Landeros JF +5 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
H∞ Control for Mixed‐Mode Based Switched Nonlinear Systems with Time‐Varying Delay [PDF]
, 2019 Zhen Liu, Shu Miao, Canbo Ye, Xingbo Liu
openalex +1 more source
An Experimental Study of the Relation between Mode I Fracture Toughness, KIc, and Critical Energy Release Rate, GIc. [PDF]
Materials (Basel), 2023 Qiao Y, Zhang ZX, Zhang S.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source