Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A comparative study of machine learning methods for predicting mode I and II brittle fracture in notched bend specimens. [PDF]
Li L, Isleem HF, Khishe M, Tejani GG.
europepmc +1 more source
A Modified Mean Stress Criterion for Considering Size Effects on Mode I Fracture Estimation of Rounded-Tip V-Notched Polymeric Specimens. [PDF]
Torabi AR +3 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Mode I Fracture of Orthotropic Laminated Composite Plates
Schulz, K.C.
doaj +1 more source
An Inverse Analysis of Interfacial Parameter Values for Mode I Debonding Between Steel and Hot-Melt Adhesive. [PDF]
Shi J +5 more
europepmc +1 more source
Mode I and II Wear in Ceramic on Ceramic Total Hip Arthroplasty: A Case Report. [PDF]
Mohan K +3 more
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Mode of action of iron (III) chelators as antimalarials: I. Membrane permeation properties and cytotoxic activity [PDF]
SD Lytton +6 more
openalex +1 more source
Investigation of fracture properties of mode I fracture in heat-treated granite. [PDF]
Niu S, Wu J, Chen S, Zhao J.
europepmc +1 more source

