Results 81 to 90 of about 5,233,866 (349)
High confinement regimes on SPARC: operational conditions for access and avoidance
This work examines H-mode and I-mode access on the SPARC tokamak, combining new simulations of core L-mode power balance with the best empirical scalings available for L–H and L–I thresholds.
J.W. Hughes +8 more
doaj +1 more source
Criterion for mixed mode fracture in composite bonded joints [PDF]
A study was undertaken to characterize the debond growth mechanism of adhesively bonded composite joints under mode I, mixed mode I-II, and mode II static loadings. The bonded system consisted of graphite-epoxy composite adherends bonded with a toughened
Kochhar, N. K., Mall, S.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Observations ofp‐Mode/s‐Mode Conversion in Magnetic Fields and Absorption ofp‐Modes by Sunspots
We decomposed the oscillations inside the annular region surrounding a sunspot (excluding the spot itself) into incoming waves (waves that propagate toward the spot) and outgoing waves (away from the spot) under a cylindrical coordinate system. We made the same decomposition for the oscillations in the annular region surrounding a spotless area ...
openaire +1 more source
Improved Calculation of Vibrational Mode Lifetimes in Anharmonic Solids - Part I: Theory
We propose here a formal foundation for practical calculations of vibrational mode lifetimes in solids. The approach is based on a recursion method analysis of the Liouvillian. From this we derive the lifetime of a vibrational mode in terms of moments of
Barenblatt +30 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A mixed-mode bending apparatus for delamination testing [PDF]
A mixed-mode delamination test procedure was developed combining double cantilever beam mode I loading and end notch flexure mode II loading on a split unidirectional laminate.
Crews, John H., Jr., Reeder, James R.
core +1 more source

