Determination of Fracture Mechanism and Mode II Fracture Toughness of Red Sandstone Subjected to Compressive-Shear Loading. [PDF]
Lei CH +5 more
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Impact of adverse environmental conditions on the fatigue behavior of carbon epoxy adhesive joints under mode II fracture. [PDF]
Vigón P +3 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Estimation of Crack Tip Position in Adhesively Bonded Joints Subjected to Mode II Fatigue Loading. [PDF]
Mehrabi M +3 more
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Environmental Effects of Moisture and Elevated Temperatures on the Mode I and Mode II Interlaminar Fracture Toughness of a Toughened Epoxy Carbon Fibre Reinforced Polymer. [PDF]
Williams A, Hamerton I, Allegri G.
europepmc +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Transverse Multibunch Head-Tail Mode Growth Rates in the PEP-II B-Factory
The growth rates for the transverse multibunch head-tail modes (m = 1) are computed for the PEP-II B-Factory, including e#ects of multibunch mode coupling. The growth rates are found to be significantly above the radiation damping rate. The primary cause
Pep-ii B-factory, Scott Berg
core
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source

