Results 51 to 60 of about 548,685 (259)

Mixed-mode I/III fracture toughness of polymer matrix composites toughened with waste particles

open access: yesScience and Engineering of Composite Materials, 2018
Fracture toughness of particle-filled polymer composite beams with different particle content for varying of crack inclination angles was investigated in mode I and mode III loading conditions.
Alsaadi Mohamad   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The effect of non-singular term (T-stress) on mode I/III cracking parameters of brittle materials, Numerical and experimental study using different beam and disc shape specimens made of marble rock

open access: yesForces in Mechanics
This study focuses on less-studied mode I/III fracture cracking behaviour. Seven specimens (ENDC, DNDC, SCB, ENDB, ATPB, TPB-IC, and SENB) were analyzed numerically and experimentally. Results show in pure mode-I, the specimens show identical KIc values (
Amir Mousavi   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Mode I+II Fatigue Crack Growth Delay by Stop-Holes

open access: yesJournal of Aerospace Technology and Management, 2018
The technique of retarding the growth of fatigue cracks by drilling holes on the crack tip is well known. Most of the research works on this subject are limited to fatigue cracks subjected to mode I loading conditions.
Dimitrios G. Pavlou
doaj  

Cohesive zone modelling of Mode III delamination using the edge crack torsion test

open access: yesJournal of Mechanical Engineering and Sciences, 2017
In the experimental studies of mode III delamination using the edge crack torsion test, the crack initiation and propagation measurement are always difficult. This information could be obtained through numerical modelling. The objective of this study is
H.A. Israr, K.J. Wong, M.N. Tamin
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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