FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Continuous-Variable Quantum Fourier Neural Operator for Solving Partial Differential Equations. [PDF]
Entropy (Basel)Marcandelli P +3 more
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Nature's Microfabricated 3D Coupled Dual-Membrane Resonators-A Dynamic Analysis of Circular Diatom Frustules. [PDF]
Micromachines (Basel)Jia Y.
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Influence of Reconstitution Methods and Diluents on the Physicochemical Characteristics of Poly-L-Lactic Acid Suspensions: An In Vitro Study. [PDF]
Polymers (Basel)Bhorntarakcharoen W +4 more
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Hydrogenation of Uracil in Solid Para-Hydrogen: Infrared Spectra of Monohydrogenated Radicals (5H-C4H5N2O2, 6H-C4H5N2O2, and 4OH-C4H5N2O2) and Their Implications for RNA-Related Chemistry in the Interstellar Medium. [PDF]
J Phys Chem AJoshi PR, Tripathi MK, Lee YP.
europepmc +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Chiral-Nematic Lattice Instability in Charge Density Wave of 1T-TiSe<sub>2</sub>. [PDF]
Adv Sci (Weinh)Alghifari AA, Do E, Park JW, Yeom HW.
europepmc +1 more source