Results 61 to 70 of about 198,137 (312)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Mixed Modes of Innovation [PDF]
OECD Science, Technology and Industry Working Papers, 2012 This study uses exploratory data analysis techniques to develop typologies of innovation modes or strategies for groups of firms. Analysing micro-level survey data from 18 countries we identify five innovation modes. The coherence and relevance of the innovation modes is tested by using them as explanatory factors in equations explaining economic ...
openaire +1 more source
Numerical analysis of four-wave mixing between 2 ps mode-locked laser pulses in a tensile-strained bulk SOA [PDF]
, 2007 A numerical model of four-wave mixing between 2-ps pulses in a tensile-strained bulk semiconductor optical amplifier is presented. The model utilizes a modified Schrodinger equation to model the pulse propagation. The Schrodinger equation parameters such
Reid, Douglas A. +7 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Effect of Bottom Blowing Mode on Fluid Flow and Mixing Behavior in Converter
Metals, 2022 Bottom blowing agitation plays a crucial role in improving the reaction kinetics condition of molten bath during the steelmaking process. Herein, the influence of bottom blowing mode on the flow and mixing characteristics of molten bath and the abrasion ...
Jiankun Sun +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Effects of mixing modes on nonresponse and measurement error in an economic panel survey
Journal for Labour Market Research, 2023 Numerous panel surveys around the world use multiple modes of data collection to recruit and interview respondents. Previous studies have shown that mixed-mode data collection can improve response rates, reduce nonresponse bias, and reduce survey costs ...
Joseph W. Sakshaug +2 more
doaj +1 more source
Degeneration of flow pattern in acousto-elastic flow through sharp-edge microchannels
Ultrasonics Sonochemistry, 2023 Acoustic streaming (AS) is the steady time-averaged flow generated by acoustic field, which has been widely used in enhancing mixing and particle manipulation.
Yuwen Lu +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Applied Sciences, 2023 The mixing and processing of high-viscosity materials play a pivotal role in composite material processing. In this context, the internal meshing screw mixer, rooted in volume extensional rheology, offers distinct advantages, including heightened mixing ...
Yinghai Hao +9 more
doaj +1 more source