Results 51 to 60 of about 2,001 (215)

Variable Filtered-Waveform Variational Mode Decomposition and Its Application in Rolling Bearing Fault Feature Extraction

Entropy
Variational Mode Decomposition (VMD) serves as an effective method for simultaneously decomposing signals into a series of narrowband components. However, its theoretical foundation, the classical Wiener filter, exhibits limited adaptability when applied
Nuo Li, Hang Wang
doaj   +1 more source

Numerical Investigation on Flow Structures and Mixing Performances of Vector-Controlled Free Jet using DNS

Journal of Fluid Science and Technology, 2011
In order to develop a new mixing procedure, we conduct DNS (direct numerical simulation) of vector controlled free jets. The inflow velocity of jet is periodically oscillated perpendicular to the jet axis.
Koichi TSUJIMOTO, Koji AO, Toshihiko SHAKOUCHI, Toshitake ANDO   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Foreground Mitigation in Cosmological 21 cm Observations: From Component Separation to End-to-End Inference

Universe
Redshifted 21 cm observations can trace neutral hydrogen from Cosmic Dawn and the Epoch of Reionization to lower-redshift large-scale structure, but foreground emission exceeds the cosmological fluctuations by several orders of magnitude.
Le Zhang
doaj   +1 more source

Mixed Modes of Innovation [PDF]

OECD Science, Technology and Industry Working Papers, 2012
This study uses exploratory data analysis techniques to develop typologies of innovation modes or strategies for groups of firms. Analysing micro-level survey data from 18 countries we identify five innovation modes. The coherence and relevance of the innovation modes is tested by using them as explanatory factors in equations explaining economic ...
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mixed-Mode and Mixed-Device Surveys

, 2017
Online surveys are one of the most prominent data collection methods in Europe and the USA. Not only are they fast and cheap, data quality in well-designed online surveys is high, especially when sensitive questions are asked. Disadvantages are the threat of undercoverage, as not everyone has Internet access, and high nonresponse.
de Leeuw, E.D., Toepoel, V.
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source