Results 41 to 50 of about 186,905 (264)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Variable Filtered-Waveform Variational Mode Decomposition and Its Application in Rolling Bearing Fault Feature Extraction

Entropy
Variational Mode Decomposition (VMD) serves as an effective method for simultaneously decomposing signals into a series of narrowband components. However, its theoretical foundation, the classical Wiener filter, exhibits limited adaptability when applied
Nuo Li, Hang Wang
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Effect of Bottom Blowing Mode on Fluid Flow and Mixing Behavior in Converter

Metals, 2022
Bottom blowing agitation plays a crucial role in improving the reaction kinetics condition of molten bath during the steelmaking process. Herein, the influence of bottom blowing mode on the flow and mixing characteristics of molten bath and the abrasion ...
Jiankun Sun, Jiangshan Zhang, Wenhui Lin, Xiaoming Feng, Qing Liu   +4 more
doaj   +1 more source

Tracking text in mixed-mode documents [PDF]

Proceedings of the ACM conference on Document processing systems - DOCPROCS '88, 1988
This paper describes a method for extracting arbitrarily oriented text in documents containing both text and graphics. The technique presented is inspired by the tracking algorithms frequently found in raster to vector conversion systems. By identifying text components in the document, reducing the resolution of the image by the size of the characters,
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Effects of mixing modes on nonresponse and measurement error in an economic panel survey

Journal for Labour Market Research, 2023
Numerous panel surveys around the world use multiple modes of data collection to recruit and interview respondents. Previous studies have shown that mixed-mode data collection can improve response rates, reduce nonresponse bias, and reduce survey costs ...
Joseph W. Sakshaug, Jonas Beste, Mark Trappmann   +2 more
doaj   +1 more source

Degeneration of flow pattern in acousto-elastic flow through sharp-edge microchannels

Ultrasonics Sonochemistry, 2023
Acoustic streaming (AS) is the steady time-averaged flow generated by acoustic field, which has been widely used in enhancing mixing and particle manipulation.
Yuwen Lu, Wei Tan, Zhifang Liu, Shuoshuo Mu, Guorui Zhu   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source