Results 101 to 110 of about 2,883,227 (296)

The Measurement and Elimination of Mode Splitting: From the Perspective of the Partly Ensemble Empirical Mode Decomposition

open access: yesComplexity, 2018
The problems of mode mixing, mode splitting, and pseudocomponents caused by intermittence or white noise signals during empirical mode decomposition (EMD) are difficult to resolve. The partly ensemble EMD (PEEMD) method is introduced first.
Bin Liu   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Revisit ion-mixing mode

open access: yes, 2018
Ion mixing mode is revisited in the case of positive density gradient taking account of toroidal curvature. It is found that there are two unstable modes, namely, ion mixing mode and electron drift wave.
Scott, Bruce   +17 more
core  

Crack Detection of Turnout Straight Switch Rail Bottom Based on Nonlinear Ultrasonic Frequency Mixing Technology

open access: yesUrban Rail Transit
Nonlinear ultrasonic frequency mixing exhibits high sensitivity and good localization capability for closed cracks. In this paper, nonlinear ultrasonic frequency mixing technology is used to investigate the contact acoustic nonlinearity phenomenon in ...
Chenyang Hu   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Mode mixing problem in empirical mode decomposition

open access: yes, 2018
Deneysel Mod Ayrıştırması (EMD), bir çok alanda doğrusal olmayan ve durağan olmayan zaman serisi verilerini analiz etmek için özellikle son yıllarda yaygın olarak kullanılmıştır.
MUHAMMED I JAITEH
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Parametric mode mixing in asymmetric doubly clamped beam resonators

open access: yesNew Journal of Physics, 2013
A model for the microscopic mechanism of parametric mixing between different modes in a single doubly clamped beam resonator is presented. Sinusoidal tension modulation along the beam axis at the frequency difference between two oscillation modes mixes ...
Hiroshi Yamaguchi, Imran Mahboob
doaj   +1 more source

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