Results 51 to 60 of about 2,883,227 (296)

A Parameterization of Local and Remote Tidal Mixing

open access: yesJournal of Advances in Modeling Earth Systems, 2020
Vertical mixing is often regarded as the Achilles' heel of ocean models. In particular, few models include a comprehensive and energy‐constrained parameterization of mixing by internal ocean tides.
C. deLavergne   +9 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The research progress of empirical mode decomposition and mode mixing elimination

open access: yesDianzi Jishu Yingyong, 2019
The Empirical Mode Decomposition(EMD) algorithm proposed by Huang is a data driven adaptive analysis method for nonlinear time-varying signals. The signals can be decomposed into a few Intrinsic Mode Functions(IMFs) components with physical meaning ...
Dai Ting   +5 more
doaj   +1 more source

[Multilingualism and Mixed-Mode Communication

open access: yes, 2023
Like other disciplines, the field of sociolinguistics is not a homogenous one. It rather comes in three “loosely connected waves” (Eckert 2012) with each wave applying specific sets of methods. How can we use methodological triangulation and combine these methods, both quantitative and qualitative in nature, to integrate the three waves of ...
openaire   +2 more sources

Mixed-Mode Pandemic Modeling [PDF]

open access: yes2019 Winter Simulation Conference (WSC), 2019
This paper describes a mixed mode approach to simulating a global pandemic. It describes the architectural and design decisions as well as the data sources, development tools and processes in each of the three simulation domains - System Dynamics (SD), Discrete Event Simulation (DES) and Agent-Based Modeling (ABM). The encompassing model uses a network
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Mixing Process Influenced by Wall Jet-Induced Shock Waves in Supersonic Flow

open access: yesApplied Sciences, 2022
With the development of hypersonic air-breathing propulsion systems, such as the supersonic combustion ramjet (Scramjet) and rocket-based combined cycle (RBCC) engines, the mixing process of supersonic airstream with fuel in the engine combustor has been
Ji Zhang   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Self-Mixing Diode Laser Interferometry [PDF]

open access: yes, 2010
Self-mixing interferometry in a laser diode is a very powerful tool in measurement science. The Self-mixing interferometer is a very robust and low cost interferometer with extreme simplicity in alignment and setup.
Shrestha, Pawan Kumar
core  

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