Results 61 to 70 of about 185,471 (264)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Ensemble All Time-Scale Decomposition Method and Its Application in Bevel Gear Fault Diagnosis
SensorsAll time-scale decomposition (ATD) is a non-parametric adaptive signal decomposition method, which relies on zero-crossing points and extreme points to jointly construct the baseline, achieving the suppression of modal mixing caused by the proximity of ...
Zhengyang Cheng +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Deep Neural Network-Based Empirical Mode Decomposition for Motor Imagery EEG Classification
IEEE Transactions on Neural Systems and Rehabilitation EngineeringMotor imagery refers to the brain’s response during the mental simulation of physical activities, which can be detected through electroencephalogram (EEG) signals.
Hyunsoo Yu +5 more
doaj +1 more source
Chinese Journal of Mechanical Engineering, 2019 Based on Multi-Masking Empirical Mode Decomposition (MMEMD) and fuzzy c-means (FCM) clustering, a new method of wind turbine bearing fault diagnosis FCM-MMEMD is proposed, which can determine the fault accurately and timely.
Yongtao Hu +5 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
All-optical mode conversion via spatially multimode four-wave mixing
New Journal of Physics, 2016 We experimentally demonstrate the conversion of a Gaussian beam to an approximate Bessel–Gauss mode by making use of a non-collinear four-wave mixing (4WM) process in hot atomic vapor.
Onur Danaci +2 more
doaj +1 more source
IEEE Access, 2018 The empirical mode decomposition (EMD) is an established method for the time-frequency analysis of nonlinear and nonstationary signals. However, one major drawback of the EMD is the mode mixing effect.
Yung-Hung Wang, Kun Hu, Men-Tzung Lo
doaj +1 more source