Results 71 to 80 of about 1,155,111 (306)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Factors That Impact Student Performance in a Course Sequence [PDF]

open access: yes, 2014
On-line courses have become an important component of the delivery of courses in all areas of education. The validity of online delivery is challenged if Web students perform poorly in subsequent major courses.
Fustos, Janos   +7 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Women’s Knowledge, Perceptions, And Potential Demand Towards Caesarean Section

open access: yesNational Journal of Community Medicine, 2011
In today’s situation when the access to obstetric care is growing day by day there has been a concern over the rising caesarean rates over the world. A cross-sectional study was undertaken with an objective to determine the level of knowledge, attitudes,
Ajeet Saoji   +3 more
doaj  

Mode of Delivery in Premature Neonates: Does It Matter?

open access: yesAmerican Journal of Perinatology Reports, 2016
Objective Despite the current prevalence of preterm births, no clear guidelines exist on the optimal mode of delivery. Our objective was to investigate the effects of mode of delivery on neonatal outcomes among premature infants in a large cohort.
Diana A. Racusin   +4 more
doaj   +1 more source

Hybrid Course Delivery: Impact on Learning and Assessment [PDF]

open access: yes, 2015
Technology is influencing education, blurring the boundaries of delivery modes. A combination between online and traditional teaching style, the hybrid/blended course, may present a solution with many benefits.
Hamza-Lup, Felix G, White, Stephen
core  

Why are health care interventions delivered over the internet? : a systematic review of the published literature [PDF]

open access: yes, 2006
Background: As Internet use grows, health interventions are increasingly being delivered online. Pioneering researchers are using the networking potential of the Internet, and several of them have evaluated these interventions. Objective: The objective
Griffiths, Frances   +4 more
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Design and Assessment for Hybrid Courses: Insights and Overviews [PDF]

open access: yes, 2015
Technology is influencing education, providing new delivery and assessment models. A combination between online and traditional course, the hybrid (blended) course, may present a solution with many benefits as it provides a gradual transition towards ...
Hamza-Lup, Felix G., White, Stephen
core  

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