Results 31 to 40 of about 9,098,363 (304)

Model-Based Design of Growth-Attenuated Viruses

PLoS Computational Biology, 2005
Live-virus vaccines activate both humoral and cell-mediated immunity, require only a single boosting, and generally provide longer immune protection than killed or subunit vaccines. However, growth of live-virus vaccines must be attenuated to minimize their potential pathogenic effects, and mechanisms of attenuation by conventional serial-transfer ...
Kwang-Il Lim, Tobias Lang, Vy Lam, John Yin   +3 more
openaire   +4 more sources

Deployment of Model-Based-Design-Adaptive Controllers for Monitoring and Control Mechatronic Devices

Applied Sciences, 2023
The modeling and control of complex, non-linear, and time-changing mechatronic systems requires complex software development. They are carried out in the prototyping phase with engineering software development tools, generating models, and control ...
Ramon Barber, David R. Rosa, Antonio Flores-Caballero, Santiago Garrido   +3 more
doaj   +1 more source

A Model-Based Approach to Automated Validation and Generation of PLC Code for Manufacturing Equipment in Regulated Environments

Applied Sciences, 2022
Validation is a critical stage of the equipment design process as it provides documentary evidence that the equipment is performing as per specification and ensures consistent product quality is maintained at all times. The advent of Industry 4.0 has led
Damian McCarthy, Dermot McMorrow, Noel P. O’Dowd, Conor T. McCarthy, Eoin P. Hinchy   +4 more
doaj   +1 more source

Simulation-Based Prediction of the Cold Start Behavior of Gerotor Pumps for Precise Design of Electric Oil Pumps

Applied Sciences
The development of electric gerotor pumps is a complex multiphysical optimization problem. To develop optimal systems, accurate simulation models are required to increase digital reliability.
Sven Schumacher, Ralf Stetter, Markus Till, Nicolas Laviolette, Benoît Algret, Stephan Rudolph   +5 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Bio-Inspired Model-Based Design and Control of Bipedal Robot

Applied Sciences, 2022
The article aims to describe stages of development of a mobile, anthropomorphic robot. The individual phases of the bio-inspired model-based design of a two-legged robot are described, from the analysis of human walking patterns, through the creation of ...
David Polakovič, Martin Juhás, Bohuslava Juhásová, Zuzana Červeňanská   +3 more
doaj   +1 more source

Model-based design of transverse wall oscillations for turbulent drag reduction

, 2012
Over the last two decades, both experiments and simulations have demonstrated that transverse wall oscillations with properly selected amplitude and frequency can reduce turbulent drag by as much as 40%.
Jovanović, Mihailo R., Moarref, Rashad
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Use of Contemporary Groups in the Construction of Multi-Environment Trial Datasets for Selection in Plant Breeding Programs

Frontiers in Plant Science, 2021
Plant breeding programs use multi-environment trial (MET) data to select superior lines, with the ultimate aim of increasing genetic gain. Selection accuracy can be improved with the use of advanced statistical analysis methods that employ informative ...
Alison Smith, Aanandini Ganesalingam, Christopher Lisle, Gururaj Kadkol, Kristy Hobson, Brian Cullis   +5 more
doaj   +1 more source

Specifying Reusable Components

, 2010
Reusable software components need expressive specifications. This paper outlines a rigorous foundation to model-based contracts, a method to equip classes with strong contracts that support accurate design, implementation, and formal verification of ...
B. Meyer, B. Meyer, C.A.R. Hoare, G.T. Leavens, J.-R. Abrial, J.A. Gougen, J.V. Guttag, K. Zee, M. Barnett   +8 more
core   +3 more sources