Results 171 to 180 of about 34,395,006 (253)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Enhancing dance learning by optimising instructional perspective: A preregistered study on the effect of dancers' viewing perspective, cognitive load and expertise. [PDF]

PLoS One
Versace E, Angioi M, Hadfield K, Gallo V, Jensen LJ, Roman J, Sheriff K, Redding E, Clarke F, Deering J, Morrissey D, Buckingham S.   +11 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

The relationship between intolerance of uncertainty and academic burnout among university students: the mediating role of future time perspective and the moderating role of psychological flexibility. [PDF]

Front Psychol
Wang Z, Wang Y, Pang M, Xu Z.
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Machine learning-based analysis of key factors and mediating mechanisms of career decision-making difficulties among higher vocational college students. [PDF]

Front Psychol
Zhang L, Wang H.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Cost-effectiveness of pembrolizumab plus chemoradiotherapy versus placebo plus chemoradiotherapy for high-risk locally advanced cervical cancer in Saudi Arabia: A model-based economic evaluation. [PDF]

Medicine (Baltimore)
Almalki ZS, Alamer AA, Alhumaid SK, Alsuhibani AA, Alghamdi BS, Alqahtani MM, Alzahrani NS, Alghamdi OA, Alanazi HH.   +8 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Should we return to probability distributions to represent interfacial reactivity? [PDF]

Nat Commun
Criscenti LJ.
europepmc   +1 more source