Results 171 to 180 of about 4,021,533 (345)

Adaptive traffic signal control using deep reinforcement learning: Toward smarter and safer urban mobility. [PDF]

PLoS One
Alanazi F, Armghan A, Tanveer M, Yousef A.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Energy-efficient path planning for Robotic Bulkhead Inspection using Residual-Enhanced UKF and Hierarchical MPC. [PDF]

PLoS One
Wang J, Li L, Gao R, Yang L.
europepmc   +1 more source

A Bibliometric Analysis on Model-based Systems Engineering

, 2021
Zihang Li, Jinzhi Lu, Guoxin Wang, Lei Feng, Didem Gürdür Broo, Dimitris Kiritsis   +5 more
openalex   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Bridging engineering and neuro-oncology: a scalable FastAPI-deployed CNN framework for real-time explainable brain tumor diagnosis. [PDF]

Front Neurosci
Nematzadeh S, Anka F, Ciftci F, Ayanoğlu KYU, Özarslan AC, Oncu E.   +5 more
europepmc   +1 more source

Achieving sustainable housing in smart cities: the role of model-based engineering in developing complex systems in line with vision 2030 [PDF]

Hassan Gbran, Waleed Alzamil
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Smart and efficient waste management through wireless IoT-enabled deep learning. [PDF]

Sci Rep
Latha P, Benni NS, Asuti MG, Thamaraiselvi K.   +3 more
europepmc   +1 more source

Multi-level architecture modelling and analysis: The case for model-based systems engineering of fusion diagnostics

T.F. Beernaert, Ad Verlaan, M. De Bock, Lucas Moser, L.F.P. Etman, I. G. J. Classen, M.R. de Baar   +6 more
openalex   +1 more source