Results 221 to 230 of about 230,174 (255)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Artificial Intelligence as the Next Visionary in Liquid Crystal Research

Advanced Functional Materials, EarlyView.
The functions of AI in the research laboratory are becoming increasingly sophisticated, allowing the entire process of hypothesis formulation, material design, synthesis, experimental design, and reiterative testing to be automated. In our work, we conceive how the incorporation of AI in the laboratory environment will transform the role and ...
Mert O. Astam, Ouassim L'Karkouri, Danqing Liu   +2 more
wiley   +1 more source

Breathable Graphene Oxide‐Polymer Composite Membranes With Two‐Step Barrier Mechanism Against Nerve Agents

Advanced Functional Materials, EarlyView.
ABSTRACT Breathable membranes that reject chemical warfare agents (CWAs) are required for next‐generation protective apparel. A dual‐function graphene oxide (GO)‐polyamine architecture is introduced that addresses the long‐standing tradeoff between vapor transmission and CWA selectivity.
Hyungjun Kim, Chanui Lee, Keunhong Jeong, Seonggi Kim, Hyunju Shin, Sunghan Kim, Youngho Jin   +6 more
wiley   +1 more source

In Situ Amidation‐Derived Interfacial Modulation for Homogeneous Ultra‐High Nanoparticle Loading Toward Robust and Flexible Piezoelectric Composites

Advanced Functional Materials, EarlyView.
Synergistic interfacial strategy between inorganic ceramic fillers and polymer chains effectively inhibit particle aggregation and interfacial incompatibility. complex covalent and non‐covalent interfacial interactions promote superior uniformity, ultra‐high ceramic filler loading, and strong grain‐to‐grain connectivity, thereby enabling the ...
HakSu Jang, In Beom Heo, Changyeon Baek, Dong Won Jeon, Donghun Lee, Nagamalleswara Rao Alluri, Hyejeong Choi, HyoMin Jeon, SungHoon Kim, Hyunseung Kim, Jihun Choi, Hyun‐Soo Chang, Chang Kyu Jeong, Min‐Ku Lee, Jun Mo Koo, Tiandong Zhang, Geon‐Tae Hwang, Sung Beom Cho, Gyoung‐Ja Lee, Hyeong Min Jin, Kwi‐Il Park   +20 more
wiley   +1 more source

Effects of Molecular Designs and Double‐Network Morphologies for Bioadhesive Semiconductors

Advanced Functional Materials, EarlyView.
This study establishes molecular‐to‐mesoscale design rules for bioadhesive semiconducting polymers (BASCs). It identifies how side‐chain length, double‐network formation, and film thickness modulate adhesion strength and electronic performance, providing insight into the rational design of intrinsically adhesive semiconductors for stable and efficient ...
Zhichang Liu, Nan Li, Yuqing Chen, Naisong Shan, Shinya Wai, Jie‐Hao Chen, Aidan Ziaja, Shrayesh N. Patel, Sihong Wang   +8 more
wiley   +1 more source

Large language models show Dunning-Kruger-like effects in multilingual fact-checking. [PDF]

Sci Rep
Qazi IA, Khan Z, Ghani A, Raza AA, Qazi ZA, Sajjad W, Ali A, Javaid A, Sohail MA, Azeemi AH.   +9 more
europepmc   +1 more source

Development and validation of a fentanyl quantification model for drug checking services. [PDF]

Drug Alcohol Depend Rep
Tobias S, Guzman SM, Hein JE, Ti L.
europepmc   +1 more source

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Model Checking

Informatik-Spektrum, 2004
Die Gewahrleistung der korrekten Funktionsweise von Hard- und Software ist ein entscheidender Faktor bei der heutigen Systementwicklung. Dies trifft ganz besonders auf das Gebiet der sog. "sicherheitskritischen" Systeme zu, bei dem ein Systemversagen Menschenleben gefahrden kann.
Ralf Buschermöhle, Mark Brörkens, Ingo Brückner, Werner Damm, Wilhelm Hasselbring, Bernhard Josko, Christoph Schulte, Thomas Wolf   +7 more
openaire   +2 more sources