Results 71 to 80 of about 230,174 (255)

LTL Model Checking Based on Binary Classification of Machine Learning

IEEE Access, 2019
Linear Temporal Logic (LTL) Model Checking (MC) has been applied to many fields. However, the state explosion problem and the exponentially computational complexity restrict the further applications of LTL model checking.
Weijun Zhu, Huanmei Wu, Miaolei Deng
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Counterexample-Preserving Reduction for Symbolic Model Checking

Journal of Applied Mathematics, 2014
The cost of LTL model checking is highly sensitive to the length of the formula under verification. We observe that, under some specific conditions, the input LTL formula can be reduced to an easier-to-handle one before model checking. In such reduction,
Wanwei Liu, Rui Wang, Xianjin Fu, Ji Wang, Wei Dong, Xiaoguang Mao   +5 more
doaj   +1 more source

On the Complexity of ATL and ATL* Module Checking [PDF]

Electronic Proceedings in Theoretical Computer Science, 2017
Module checking has been introduced in late 1990s to verify open systems, i.e., systems whose behavior depends on the continuous interaction with the environment.
Laura Bozzelli, Aniello Murano
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Consistency checking of UML business model

Technological and Economic Development of Economy, 2011
Unified modelling language (UML) is often used in practice for modelling business system (BS) by various aspects. UML model of business system consists of different aspect models and their usage for information system (IS) design is related with ...
Olegas Vasilecas, Rūta Dubauskaitė, Rok Rupnik   +2 more
doaj   +1 more source

Model Checking Dynamic-Epistemic Spatial Logic [PDF]

, 2006
In this paper we focus on Dynamic Spatial Logic, the extension of Hennessy-Milner logic with the parallel operator. We develop a sound complete Hilbert-style axiomatic system for it comprehending the behavior of spatial operators in relation with dynamic/
Mardare, Radu, Priami, Corrado
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Bounded saturation-based CTL model checking; pp. 59–70 [PDF]

Proceedings of the Estonian Academy of Sciences, 2013
Formal verification is becoming a fundamental step of safety-critical and model-based software development. As part of the verification process, model checking is one of the current advanced techniques to analyse the behaviour of a system. Symbolic model
András Vörös, Dániel Darvas, Tamás Bartha   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source